Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Pallais, O. Kifor, Yi-Bin Chen, D. Slovik, Edward Brown (2004)
Acquired hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor.The New England journal of medicine, 351 4
F. Maritati, F. Peyronel, A. Vaglio (2020)
IgG4-related disease: a clinical perspective.Rheumatology, 59 Supplement_3
S. Hasegawa, S. Mine, S. Hagiwara (2015)
IgG4-Related Disease Combined with Autoimmune Hemolytic Anemia and Steroid-Responsive Transient HypercalcemiaClinical Medicine Insights. Case Reports, 8
A. Amirbaigloo, F. Esfahanian, Marjan Mouodi, N. Rakhshani, Mehdi Zeinalizadeh (2021)
IgG4-related hypophysitisEndocrine, 73
C. Perugino, J. Stone (2020)
IgG4-related disease: an update on pathophysiology and implications for clinical careNature Reviews Rheumatology
A. Catalano, D. Chilà, F. Bellone, G. Nicocia, G. Martino, I. Loddo, N. Morabito, S. Benvenga, S. Loddo (2018)
Incidence of hypocalcemia and hypercalcemia in hospitalized patients: Is it changing?Journal of Clinical & Translational Endocrinology, 13
B. Veress, J. Nordenström (1994)
Lymphocytic infiltration and destruction of parathyroid adenomas: a possible tumour‐specific autoimmune reaction in two cases of primary hyperparathyroidismHistopathology, 25
Taimoor Hussain, Farukhzad Hafizyar, Abdul Latif, Muzhda Mujadidi, Khalida Walizada, Zahra Mushtaq, J. Kumar (2021)
Primary hyperparathyroidism presenting with acute pancreatitis, complicated by raised IgG-4 and positive Covid-19 IgG antibodyJournal of Clinical and Translational Endocrinology: Case Reports
Minsun Jung, J. Bae, Y. Jeon, K. Jung, Sun Cho, J. Won (2019)
Parathyroid adenoma with prominent lymphocytic infiltrate having histological features highly suggestive of IgG4-related disease: a case report and literature review.Endocrine journal, 66 4
Chieko Kawakita, M. Kinomura, Y. Gon, Chika Okita, Katsuyoshi Katayama, Mana Nishikawa, N. Shimada, K. Notohara, M. Fukushima, Kenichiro Asano (2018)
A case of fatal osteolytic hypercalcemia complicated with IgG4-related ophthalmic disease leading to renal failureCEN Case Reports, 8
H. Karadeniz, A. Vaglio (2020)
IgG4-related disease: a contemporary reviewTurkish Journal of Medical Sciences, 50
J. Medina, G. Randolph, P. Angelos, M. Zafereo, R. Tufano, Luiz Kowalski, F. Montenegro, R. Owen, A. Khafif, C. Suárez, A. Shaha, J. Rodrigo, G. Krempl, A. Rinaldo, C. Silver, A. Ferlito (2021)
Primary hyperparathyroidism: Disease of diverse genetic, symptomatic, and biochemical phenotypesHead & Neck, 43
A. Gasparyan, L. Ayvazyan, H. Blackmore, G. Kitas (2011)
Writing a narrative biomedical review: considerations for authors, peer reviewers, and editorsRheumatology International, 31
(2020)
IgG4-related dis- ease: a clinical perspective. Rheumatology (Oxford) 59(Suppl 3):iii123–iii131
S Hasegawa (2015)
51Clin Med Insights Case Rep, 10
K. Kovacs, C. Bell, J. Juco, F. Rotondo, Jennifer Anderson (2007)
Parathyroid Chief Cell Adenoma Associated with Massive Chronic Parathyroiditis in a Woman with HyperparathyroidismEndocrine Pathology, 18
Immunoglobulin (Ig) G4-related disease (IgG4RD) is a chronic autoimmune disorder characterized by dense lymphoplasmacytic infiltrations and fibrosis of storiform pattern. The most typical manifestations include major salivary or lacrimal gland involvement, autoimmune pancreatitis, and retroperitoneal fibrosis. While the increase in IgG4 is the typical feature of the disease, hypercalcemia has been rarely reported in IgG4RD so far, only one of these cases has been shown parathyroid gland involvement (isolated involvement). In this study, we present a 43-year-old female patient with weight loss, pancreatic mass, lymphadenopathy, nodular lesion in the lung, hypercalcemia, and also increased level of serum IgG4. Histopathological investigation following parathyroidectomy revealed a dense lymphoplasmacytic infiltrate with an IgG4 to IgG ratio of > 50% in the fat tissue surrounding the parathyroid gland, particularly at the perivascular areas. This is the first systemic IgG4RD case in combination with hypercalcemia in the literature who was detected to have parathyroid adenoma. Our aim in this review is to emphasize that, although rarely, IgG4RD may be accompanied by hypercalcemia and parathyroid gland may be one of its target sites.
Rheumatology International – Springer Journals
Published: Jul 1, 2022
Keywords: IgG4-related disease; Hypercalcemia; Hyperparathyroidism; Parathyroid adenoma
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.