Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Herbal Medicines for Allergic Rhinitis: a Systematic Review and Meta-analysis

Herbal Medicines for Allergic Rhinitis: a Systematic Review and Meta-analysis Purpose of ReviewTo assess the effects of herbal medicine (HM) therapy in various durations and analyze the effects of HM separately by mechanism of action in the treatment of allergic rhinitis (AR).Recent FindingsThirty-two studies were included (2,697 patients, mean age 34.6 years). For the ≤ 4 weeks of treatment duration, HM brought greater benefits over placebo in reduction of total nasal symptoms score (standardized mean difference (SMD) −0.68; 95% confidence interval (CI) −0.98, −0.38; p <0.01) and improvement in Rhinoconjunctivitis Quality of Life Questionnaire score (SMD −0.53; 95% CI −0.81, −0.25; p <0.01). For the 4–12 weeks duration, total nasal symptoms score (SMD −0.22; 95%CI −0.4, −0.05; p =0.01) and Rhinoconjunctivitis Quality of Life Questionnaire score (SMD −0.48; 95% CI −0.89, −0.06; p =0.03) favored the HM. However, HM therapy for longer than 12 weeks was related to tachyphylaxis and showed no benefit over placebo in any outcomes. There was no difference between the HM and standard treatment on symptoms improvement. Anti-allergic effect, anti-inflammatory effect, anti-leukotriene effect, and anti-histaminic effect of HM were revealed. HM was safe and their adverse effects were comparable placebo.SummaryHM therapy is safe and provides better results than placebo in improving nasal symptoms and disease-specific quality of life in patients with AR. Its beneficial effects are demonstrated only in less than 12 weeks of treatment.Trial RegistrationPROSPERO ID: CRD42020168367 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

Herbal Medicines for Allergic Rhinitis: a Systematic Review and Meta-analysis

Download PDF
12 pages

Loading next page...
 
/lp/springer-journals/herbal-medicines-for-allergic-rhinitis-a-systematic-review-and-meta-H0FdLIlota

References (59)

Publisher
Springer Journals
Copyright
Copyright © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-021-00999-9
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewTo assess the effects of herbal medicine (HM) therapy in various durations and analyze the effects of HM separately by mechanism of action in the treatment of allergic rhinitis (AR).Recent FindingsThirty-two studies were included (2,697 patients, mean age 34.6 years). For the ≤ 4 weeks of treatment duration, HM brought greater benefits over placebo in reduction of total nasal symptoms score (standardized mean difference (SMD) −0.68; 95% confidence interval (CI) −0.98, −0.38; p <0.01) and improvement in Rhinoconjunctivitis Quality of Life Questionnaire score (SMD −0.53; 95% CI −0.81, −0.25; p <0.01). For the 4–12 weeks duration, total nasal symptoms score (SMD −0.22; 95%CI −0.4, −0.05; p =0.01) and Rhinoconjunctivitis Quality of Life Questionnaire score (SMD −0.48; 95% CI −0.89, −0.06; p =0.03) favored the HM. However, HM therapy for longer than 12 weeks was related to tachyphylaxis and showed no benefit over placebo in any outcomes. There was no difference between the HM and standard treatment on symptoms improvement. Anti-allergic effect, anti-inflammatory effect, anti-leukotriene effect, and anti-histaminic effect of HM were revealed. HM was safe and their adverse effects were comparable placebo.SummaryHM therapy is safe and provides better results than placebo in improving nasal symptoms and disease-specific quality of life in patients with AR. Its beneficial effects are demonstrated only in less than 12 weeks of treatment.Trial RegistrationPROSPERO ID: CRD42020168367

Journal

Current Allergy and Asthma Reports – Springer Journals

Published: Mar 25, 2021

There are no references for this article.