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Going electric

Going electric research highlights DNA ORIGAMI SPIN TRANSISTORS assay relies on fluorescence signals only resulting from dimeric interaction between Slider and hinge joints Going electric the amyloidogenic peptides, which are fused, Proc. Natl Acad. Sci. USA http://doi.org/x4p (2015) Nature Nanotech. 10, 35–39 (2015) via a linker, to fragments of a split mCherry Many efforts have been devoted to the protein. The assay identified compounds development of spin field-effect transistors already known to inhibit aggregation of since they were proposed by Datta and Das amyloid peptides and these compounds in 1990. Their idea was to inject and detect were then shown to increase the viability of spin-polarized currents in a two-dimensional pancreatic cells in the presence of amyloid gas of a semiconductor heterostructure by fibrils in a dose-dependent manner. The using magnetic electrodes, and to control the correlation between the screening process spin polarization with electric fields, which and in vitro results indicates that these would allow the encoding of information. dimeric interactions are an important target The fabrication of the device is challenging for drug development. The assay has the however due to reduced spin-injection potential to be automated, thus permitting efficiencies and spin-depolarization high-throughput screening of compounds. AS Mechanical machines combine http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Materials Springer Journals

Going electric

Nature Materials , Volume 14 (2) – Jan 23, 2015

Going electric

Abstract

research highlights DNA ORIGAMI SPIN TRANSISTORS assay relies on fluorescence signals only resulting from dimeric interaction between Slider and hinge joints Going electric the amyloidogenic peptides, which are fused, Proc. Natl Acad. Sci. USA http://doi.org/x4p (2015) Nature Nanotech. 10, 35–39 (2015) via a linker, to fragments of a split mCherry Many efforts have been devoted to the protein. The assay identified compounds development of spin field-effect transistors already known to...
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References (1)

Publisher
Springer Journals
Copyright
Copyright © 2015 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Materials Science; Materials Science, general; Optical and Electronic Materials; Biomaterials; Nanotechnology; Condensed Matter Physics
ISSN
1476-1122
eISSN
1476-4660
DOI
10.1038/nmat4207
Publisher site
See Article on Publisher Site

Abstract

research highlights DNA ORIGAMI SPIN TRANSISTORS assay relies on fluorescence signals only resulting from dimeric interaction between Slider and hinge joints Going electric the amyloidogenic peptides, which are fused, Proc. Natl Acad. Sci. USA http://doi.org/x4p (2015) Nature Nanotech. 10, 35–39 (2015) via a linker, to fragments of a split mCherry Many efforts have been devoted to the protein. The assay identified compounds development of spin field-effect transistors already known to inhibit aggregation of since they were proposed by Datta and Das amyloid peptides and these compounds in 1990. Their idea was to inject and detect were then shown to increase the viability of spin-polarized currents in a two-dimensional pancreatic cells in the presence of amyloid gas of a semiconductor heterostructure by fibrils in a dose-dependent manner. The using magnetic electrodes, and to control the correlation between the screening process spin polarization with electric fields, which and in vitro results indicates that these would allow the encoding of information. dimeric interactions are an important target The fabrication of the device is challenging for drug development. The assay has the however due to reduced spin-injection potential to be automated, thus permitting efficiencies and spin-depolarization high-throughput screening of compounds. AS Mechanical machines combine

Journal

Nature MaterialsSpringer Journals

Published: Jan 23, 2015

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