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Genetics of Circadian and Sleep Measures in Adults: Implications for Sleep Medicine

Genetics of Circadian and Sleep Measures in Adults: Implications for Sleep Medicine Purpose of ReviewIn this review, we comprehensively discuss recent reports of heritability and genetic associations using candidate gene and genome-wide association (GWA) approaches in circadian and sleep phenotypes in adults, including chronotype (morningness-eveningness), sleep duration and daytime sleepiness, circadian rhythm sleep-wake disorders, and insomnia.Recent FindingsRecent findings derive from GWA studies with objective measures and candidate gene studies examining the role of genetic ancestry and health disparities for sleep and circadian measures.SummaryThe discovery of key, novel genetic markers using various methods has critical implications for future research in terms of identification, treatment, and countermeasures in the field of sleep medicine. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Sleep Medicine Reports Springer Journals

Genetics of Circadian and Sleep Measures in Adults: Implications for Sleep Medicine

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Publisher
Springer Journals
Copyright
Copyright © Springer Nature Switzerland AG 2020
eISSN
2198-6401
DOI
10.1007/s40675-020-00165-z
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewIn this review, we comprehensively discuss recent reports of heritability and genetic associations using candidate gene and genome-wide association (GWA) approaches in circadian and sleep phenotypes in adults, including chronotype (morningness-eveningness), sleep duration and daytime sleepiness, circadian rhythm sleep-wake disorders, and insomnia.Recent FindingsRecent findings derive from GWA studies with objective measures and candidate gene studies examining the role of genetic ancestry and health disparities for sleep and circadian measures.SummaryThe discovery of key, novel genetic markers using various methods has critical implications for future research in terms of identification, treatment, and countermeasures in the field of sleep medicine.

Journal

Current Sleep Medicine ReportsSpringer Journals

Published: Mar 20, 2020

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