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Gemcitabine in Combination with Paclitaxel in the First-Line Treatment of Metastatic Breast Cancer

Gemcitabine in Combination with Paclitaxel in the First-Line Treatment of Metastatic Breast Cancer Am J Cancer 2005; 4 (5): 334-335 GUEST COMMENTARIES 1175-6357/05/0005-0334/$34.95/0 © 2005 Adis Data Information BV. All rights reserved. Several phase II studies examining the use of gemcitabine plus Gemcitabine in Combination with Paclitaxel paclitaxel in heavily pre-treated patients or as first-line treatment in the First-Line Treatment of Metastatic reported promising efficacy with a favourable toxicity profile. Breast Cancer A phase III study comparing the combination of gemcitabine A Viewpoint by Carlos Delfino plus paclitaxel with paclitaxel alone as first-line treatment for Hospital Privado de Comunidad, Mar del Plata, Argentina metastatic breast cancer in 529 patients who had received prior adjuvant anthracycline treatment was presented at the 2003 and In the management of advanced breast cancer, chemotherapy is 2004 American Society of Clinical Oncology meetings. The com- considered palliative and not curative but has improved the prog- bination arm reported higher response rates and longer survival nosis for these patients. (interim analysis). There was more haematologic toxicity and Anthracyclines and taxanes are among the most active chemo- more fatigue in the combination arm. In addition, the mean Rotter- therapeutic drugs for the treatment of breast cancer. With the dam Symptom Checklist global quality of life score was signifi- increasing http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cancer Springer Journals

Gemcitabine in Combination with Paclitaxel in the First-Line Treatment of Metastatic Breast Cancer

American Journal of Cancer , Volume 4 (5) – Aug 10, 2012

Gemcitabine in Combination with Paclitaxel in the First-Line Treatment of Metastatic Breast Cancer

Abstract

Am J Cancer 2005; 4 (5): 334-335 GUEST COMMENTARIES 1175-6357/05/0005-0334/$34.95/0 © 2005 Adis Data Information BV. All rights reserved. Several phase II studies examining the use of gemcitabine plus Gemcitabine in Combination with Paclitaxel paclitaxel in heavily pre-treated patients or as first-line treatment in the First-Line Treatment of Metastatic reported promising efficacy with a favourable toxicity profile. Breast Cancer A phase III study comparing the combination of gemcitabine...
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Publisher
Springer Journals
Copyright
Copyright © 2005 by Adis Data Information BV
Subject
Pharmacy; Pharmacy
ISSN
1175-6357
DOI
10.2165/00024669-200504050-00009
Publisher site
See Article on Publisher Site

Abstract

Am J Cancer 2005; 4 (5): 334-335 GUEST COMMENTARIES 1175-6357/05/0005-0334/$34.95/0 © 2005 Adis Data Information BV. All rights reserved. Several phase II studies examining the use of gemcitabine plus Gemcitabine in Combination with Paclitaxel paclitaxel in heavily pre-treated patients or as first-line treatment in the First-Line Treatment of Metastatic reported promising efficacy with a favourable toxicity profile. Breast Cancer A phase III study comparing the combination of gemcitabine A Viewpoint by Carlos Delfino plus paclitaxel with paclitaxel alone as first-line treatment for Hospital Privado de Comunidad, Mar del Plata, Argentina metastatic breast cancer in 529 patients who had received prior adjuvant anthracycline treatment was presented at the 2003 and In the management of advanced breast cancer, chemotherapy is 2004 American Society of Clinical Oncology meetings. The com- considered palliative and not curative but has improved the prog- bination arm reported higher response rates and longer survival nosis for these patients. (interim analysis). There was more haematologic toxicity and Anthracyclines and taxanes are among the most active chemo- more fatigue in the combination arm. In addition, the mean Rotter- therapeutic drugs for the treatment of breast cancer. With the dam Symptom Checklist global quality of life score was signifi- increasing

Journal

American Journal of CancerSpringer Journals

Published: Aug 10, 2012

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