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From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional... A methodology for the ex ante evaluation of different processing options is proposed. Current processes for glucose oxidation and possible improvements using microreactor technology are investigated. As twofold prime research objectives, the oxidation with noble metal catalyst versus enzymatic oxidation and the oxidation under conventional process conditions versus under Novel Process Windows are explored. Operation and design of an active and stable catalyst, reactor performance, and work-up are included. This ex ante analysis gives information of the critical aspects of a process prior to technology development and facilitates the development of new process routes; especially valuable if step and paradigm changing routes are undertaken, with even no vague idea on their performance potential and with high technological risk. The methodology used for gluconic acid production will be transferred to other chemicals which have the potential in using microreactor technology and Novel Process Windows. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Flow Chemistry Springer Journals

From a Review of Noble Metal versus Enzyme Catalysts for Glucose Oxidation Under Conventional Conditions Towards a Process Design Analysis for Continuous-flow Operation

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Publisher
Springer Journals
Copyright
Copyright © Akadémiai Kiadó 2011
ISSN
2062-249X
eISSN
2063-0212
DOI
10.1556/jfchem.2011.00005
Publisher site
See Article on Publisher Site

Abstract

A methodology for the ex ante evaluation of different processing options is proposed. Current processes for glucose oxidation and possible improvements using microreactor technology are investigated. As twofold prime research objectives, the oxidation with noble metal catalyst versus enzymatic oxidation and the oxidation under conventional process conditions versus under Novel Process Windows are explored. Operation and design of an active and stable catalyst, reactor performance, and work-up are included. This ex ante analysis gives information of the critical aspects of a process prior to technology development and facilitates the development of new process routes; especially valuable if step and paradigm changing routes are undertaken, with even no vague idea on their performance potential and with high technological risk. The methodology used for gluconic acid production will be transferred to other chemicals which have the potential in using microreactor technology and Novel Process Windows.

Journal

Journal of Flow ChemistrySpringer Journals

Published: Jan 1, 2011

Keywords: glucose oxidation; process intensification; falling film microreactor; novel process windows; glucose oxidase

References