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Purpose of Review To increase understanding of food protein-induced enterocolitis syndrome (FPIES), a non-immunoglobulin E (IgE)-mediated reaction to food, by reviewing a growing body of literature, including recently published international consensus guidelines. Recent Findings FPIES primarily affects infants and young children and is characterized by the delayed onset of gastrointestinal symptoms, predominantly repetitive vomiting, in response to a trigger food. Symptoms are often severe and can lead to shock. Diagnosis can be challenging due to a wide differential diagnoses and lack of disease biomarkers. FPIES is a clinical diagnosis, with allergy testing playing a very limited role, if any. Medically supervised oral food challenges are used to monitor resolution of disease, which generally occurs in early childhood. Summary FPIES is an important condition presenting to clinicians in a variety of settings. Recent international consensus guidelines and a growing body of literature can better equip practitioners to care for these often-challenging patients. . . . Keywords FPIES Food protein-induced enterocolitis syndrome Food allergy Non-IgE-mediated food allergy Introduction guidelines for FPIES were released. The guidelines focus on the diagnosis and management of FPIES and assist clinicians in Food protein-induced enterocolitis syndrome (FPIES) is an in- the care of patients with this
Current Allergy and Asthma Reports – Springer Journals
Published: Apr 6, 2018
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