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Oncol Ther (2016) 4:103–116 DOI 10.1007/s40487-016-0020-4 ORIGINAL RESEARCH Factors Impacting Treatment Choice in the First-Line Treatment of Colorectal Cancer . . . Lourens T. Bloem Richard De Abreu Lourenc ¸o Melvin Chin Brett Ly Marion Haas Received: March 4, 2016 / Published online: May 11, 2016 The Author(s) 2016. This article is published with open access at Springerlink.com in the Sydney metropolitan area, Australia were ABSTRACT identified using the hospital’s database Introduction: To investigate the factors that MOSAIQ . The electronic medical record of affect the choice of 5-fluorouracil (5-FU) or its each patient was manually reviewed to extract oral alternative, capecitabine, as first-line factors potentially affecting treatment choice. treatment in patients with colorectal cancer Logistic regression was used to assess which (CRC). patient and/or treatment factors could explain Methods: Patients treated with 5-FU or the choice between 5-FU or capecitabine. Where capecitabine for CRC between January 1, 2011 it was available in the medical correspondence, and December 31, 2013 in a teaching hospital the explicit reason for the choice made was extracted. Enhanced content To view enhanced content for this Results: 170 CRC patients were included; 119 article go to www.medengine.com/Redeem/ 05C4F060100E857A. on 5-FU, and 51 on capecitabine.
Oncology and Therapy – Springer Journals
Published: May 11, 2016
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