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S. Hiltbrunner, P. Larssen, M. Eldh, M. Martínez-Bravo, A. Wagner, M. Karlsson, S. Gabrielsson (2016)
Exosomal cancer immunotherapy is independent of MHC molecules on exosomesOncotarget, 7
Karolina Cyll, Elin Ersvær, L. Vlatkovic, M. Pradhan, W. Kildal, Marte Kjær, Andreas Kleppe, T. Hveem, B. Carlsen, Silje Gill, S. Löffeler, E. Haug, H. Wæhre, P. Sooriakumaran, H. Danielsen (2017)
Tumour heterogeneity poses a significant challenge to cancer biomarker researchBritish Journal of Cancer, 117
Arscott Wt, C. Ka (2011)
Exosome characterization from ascitic fluid holds promise for identifying markers of colorectal cancer.Biomarkers in Medicine, 5
A. Savina, M. Furlán, M. Vidal, M. Colombo (2003)
Exosome Release Is Regulated by a Calcium-dependent Mechanism in K562 Cells*Journal of Biological Chemistry, 278
B. Nabet, Yu Qiu, J. Shabason, Tony Wu, T. Yoon, Brian Kim, Joseph Benci, A. DeMichele, J. Tchou, J. Marcotrigiano, A. Minn (2017)
Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in CancerCell, 170
M. Fong, Weiying Zhou, Liang Liu, A. Alontaga, Manasa Chandra, Jonathan Ashby, A. Chow, Sean O’Connor, Shasha Li, Andrew Chin, G. Somlo, M. Palomares, Zhuo Li, Jacob Tremblay, Akihiro Tsuyada, Guoqiang Sun, M. Reid, Xiwei Wu, P. Swiderski, X. Ren, Yanhong Shi, Mei Kong, Wenwan Zhong, Yuan Chen, S. Wang (2015)
Breast cancer-secreted miR-122 reprograms glucose metabolism in pre-metastatic niche to promote metastasisNature cell biology, 17
V. Kristensen (2017)
The Antigenicity of the Tumor Cell — Context MattersThe New England Journal of Medicine, 376
C. D’Souza-Schorey, James Clancy (2012)
Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers.Genes & development, 26 12
R. Donker, J. Mouillet, T. Chu, C. Hubel, D. Stolz, A. Morelli, Y. Sadovsky (2012)
The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes.Molecular human reproduction, 18 8
M. Lentz (1989)
Continuous whole blood UltraPheresis procedure in patients with metastatic cancer.Journal of biological response modifiers, 8 5
M. Jamal-Hanjani, G. Wilson, N. Mcgranahan, N. Birkbak, T. Watkins, S. Veeriah, S. Shafi, Diana Johnson, R. Mitter, R. Rosenthal, M. Salm, S. Horswell, M. Escudero, Nik Matthews, A. Rowan, T. Chambers, D. Moore, S. Turajlic, Hang Xu, S. Lee, M. Forster, T. Ahmad, C. Hiley, C. Abbosh, M. Falzon, E. Borg, T. Marafioti, D. Lawrence, M. Hayward, S. Kolvekar, N. Panagiotopoulos, S. Janes, R. Thakrar, Asia Ahmed, F. Blackhall, Y. Summers, R. Shah, L. Joseph, A. Quinn, P. Crosbie, B. Naidu, G. Middleton, G. Langman, S. Trotter, M. Nicolson, H. Remmen, K. Kerr, M. Chetty, L. Gomersall, D. Fennell, A. Nakas, S. Rathinam, G. Anand, S. Khan, P. Russell, V. Ezhil, Babikir Ismail, Melanie Irvin-sellers, V. Prakash, J. Lester, M. Kornaszewska, R. Attanoos, Haydn Adams, H. Davies, S. Dentro, P. Tanière, B. O’Sullivan, H. Lowe, J. Hartley, N. Iles, Harriet Bell, Y. Ngai, J. Shaw, Javier Herrero, Z. Szallasi, R. Schwarz, A. Stewart, S. Quezada, J. Quesne, P. Loo, C. Dive, A. Hackshaw, C. Swanton (2017)
Tracking the Evolution of Non‐Small‐Cell Lung CancerThe New England Journal of Medicine, 376
A. Clayton, A. Turkes, H. Navabi, M. Mason, Z. Tabi (2005)
Induction of heat shock proteins in B-cell exosomesJournal of Cell Science, 118
R. Valenti, V. Huber, M. Iero, P. Filipazzi, G. Parmiani, L. Rivoltini (2007)
Tumor-released microvesicles as vehicles of immunosuppression.Cancer research, 67 7
Cunren Liu, Shaohua Yu, K. Zinn, Jianhua Wang, Liming Zhang, Yujiang Jia, J. Kappes, Stephen Barnes, R. Kimberly, W. Grizzle, Huang-Ge Zhang (2006)
Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function1The Journal of Immunology, 176
NA Rizvi, MD Hellmann, A Snyder, P Kvistborg, V Makarov, JJ Havel (2015)
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancerScience, 348
H. Peinado, M. Alečković, S. Lavotshkin, Irina Matei, B. Costa-Silva, G. Moreno-Bueno, M. Hergueta-Redondo, Caitlin Williams, G. García‐Santos, Cyrus Ghajar, Ayuko Nitadori-Hoshino, Caitlin Hoffman, K. Badal, B. Garcia, M. Callahan, Jianda Yuan, V. Martins, J. Skog, R. Kaplan, M. Brady, J. Wolchok, P. Chapman, Yibin Kang, J. Bromberg, D. Lyden (2012)
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through METNature Medicine, 18
I. Parolini, C. Federici, C. Raggi, L. Lugini, S. Palleschi, A. Milito, C. Coscia, Elisabetta Iessi, M. Logozzi, A. Molinari, M. Colone, M. Tatti, M. Sargiacomo, S. Fais (2009)
Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells*The Journal of Biological Chemistry, 284
Huang-Ge Zhang, W. Grizzle (2014)
Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions.The American journal of pathology, 184 1
A. Bardelli, K. Pantel (2017)
Liquid Biopsies, What We Do Not Know (Yet).Cancer cell, 31 2
M. Le, P. Hamar, Changying Guo, E. Basar, R. Perdigão-Henriques, L. Balaj, J. Lieberman (2014)
miR-200-containing extracellular vesicles promote breast cancer cell metastasis.The Journal of clinical investigation, 124 12
J. Park, Hongwu Tan, Arnab Datta, R. Lai, Huoming Zhang, Wei Meng, S. Lim, S. Sze (2010)
Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes*Molecular & Cellular Proteomics, 9
L. Graves, E. Ariztia, J. Navari, H. Matzel, M. Stack, D. Fishman (2004)
Proinvasive Properties of Ovarian Cancer Ascites-Derived Membrane VesiclesCancer Research, 64
J. Qu, X. Qu, Mingfang Zhao, Y. Teng, Ye Zhang, K. Hou, Youhong Jiang, Xianghong Yang, Yunpeng Liu (2009)
Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 41 12
B. Seliger (2017)
Immune modulatory microRNAs as a novel mechanism to revert immune escape of tumors.Cytokine & growth factor reviews, 36
D. Haber, V. Velculescu (2014)
Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA.Cancer discovery, 4 6
S. Melo, H. Sugimoto, Joyce O’Connell, Noritoshi Kato, A. Villanueva, A. Vidal, Le Qiu, E. Vitkin, L. Perelman, C. Melo, A. Lucci, C. Ivan, G. Calin, R. Kalluri (2014)
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.Cancer cell, 26 5
A. Orozco, D. Lewis (2010)
Flow cytometric analysis of circulating microparticles in plasmaCytometry Part A, 77A
A. Ginestra, D. Miceli, V. Dolo, F. Romano, M. Vittorelli (1999)
Membrane vesicles in ovarian cancer fluids: a new potential marker.Anticancer research, 19 4C
Aiko Sueta, Yutaka Yamamoto, M. Tomiguchi, T. Takeshita, M. Yamamoto-Ibusuki, H. Iwase (2017)
Differential expression of exosomal miRNAs between breast cancer patients with and without recurrenceOncotarget, 8
W. Arscott, K. Camphausen (2011)
EGFR isoforms in exosomes as a novel method for biomarker discovery in pancreatic cancer.Biomarkers in medicine, 5 6
D. Taylor, Ç. Gerçel-Taylor (2008)
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.Gynecologic oncology, 110 1
T. Fang, H. Lv, Guishuai Lv, Ting Li, Changzheng Wang, Qin Han, Lexing Yu, B. Su, Lin-na Guo, Shanna Huang, D. Cao, Liang Tang, Shanhua Tang, Mengchao Wu, Wen Yang, Hongyang Wang (2018)
Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancerNature Communications, 9
L. Muller, P. Simms, Chang‐Sook Hong, M. Nishimura, E. Jackson, Simon Watkins, T. Whiteside (2017)
Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanismsOncoImmunology, 6
H. Dejima, H. Iinuma, Rie Kanaoka, N. Matsutani, M. Kawamura (2017)
Exosomal microRNA in plasma as a non-invasive biomarker for the recurrence of non-small cell lung cancer.Oncology letters, 13 3
N. Rizvi, M. Hellmann, A. Snyder, P. Kvistborg, V. Makarov, J. Havel, William Lee, Jianda Yuan, P. Wong, Teresa Ho, Martin Miller, N. Rekhtman, A. Moreira, Fawzia Ibrahim, Cameron Bruggeman, Billel Gasmi, R. Zappasodi, Y. Maeda, C. Sander, E. Garon, T. Merghoub, J. Wolchok, T. Schumacher, T. Chan (2015)
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancerScience, 348
V. Martins, Marcos Dias, P. Hainaut (2013)
Tumor-cell-derived microvesicles as carriers of molecular information in cancerCurrent Opinion in Oncology, 25
Élodie Ristorcelli, E. Béraud, S. Mathieu, D. Lombardo, A. Vérine (2009)
Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticlesInternational Journal of Cancer, 125
V. Lopes-Rodrigues, V. Lopes-Rodrigues, Alessio Luca, J. Mleczko, P. Meleady, M. Henry, M. Pešić, D. Cabrera, S. Liempd, Raquel Lima, Raquel Lima, R. O'Connor, J. Falcón‐Pérez, M. Vasconcelos, M. Vasconcelos (2017)
Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesiclesScientific Reports, 7
Ayuko Hoshino, B. Costa-Silva, Tang-Long Shen, G. Rodrigues, Ayako Hashimoto, M. Mark, H. Molina, S. Kohsaka, A. Giannatale, S. Ceder, Swarnima Singh, Caitlin Williams, Nadine Soplop, K. Uryu, Lindsay Pharmer, T. King, Linda Bojmar, A. Davies, Yonathan Ararso, Tuo Zhang, Haiying Zhang, Jonathan Hernandez, Joshua Weiss, Vanessa Dumont-Cole, K. Kramer, L. Wexler, A. Narendran, G. Schwartz, J. Healey, P. Sandstrom, K. Labori, E. Kure, P. Grandgenett, M. Hollingsworth, Maria Sousa, S. Kaur, Maneesh Jain, K. Mallya, S. Batra, W. Jarnagin, M. Brady, O. Fodstad, V. Muller, K. Pantel, A. Minn, M. Bissell, B. Garcia, Yibin Kang, Vinagolu Rajasekhar, Cyrus Ghajar, Irina Matei, H. Peinado, J. Bromberg, D. Lyden (2015)
Tumour exosome integrins determine organotropic metastasisNature, 527
L. O’Driscoll (2015)
Expanding on exosomes and ectosomes in cancer.The New England journal of medicine, 372 24
Huang-Ge Zhang, W. Grizzle (2011)
Exosomes and Cancer: A Newly Described Pathway of Immune SuppressionClinical Cancer Research, 17
Yanfang Liu, Yan Gu, Yanmei Han, Qian Zhang, Zhengping Jiang, Xiang Zhang, Bo Huang, Xiaoqing Xu, Jianming Zheng, Xuetao Cao (2016)
Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils.Cancer cell, 30 2
Anuradha Sabapatha, Ç. Gerçel-Taylor, D. Taylor (2006)
Specific Isolation of Placenta‐Derived Exosomes from the Circulation of Pregnant Women and Their Immunoregulatory Consequences 1American Journal of Reproductive Immunology, 56
M. Tesselaar, F. Romijn, I. Linden, F. Prins, R. Bertina, S. Osanto (2007)
Microparticle‐associated tissue factor activity: a link between cancer and thrombosis?Journal of Thrombosis and Haemostasis, 5
Stephen Paget (1889)
THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.The Lancet, 133
J. McCready, Jessica Sims, D. Chan, D. Jay (2010)
Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activationBMC Cancer, 10
G. Deng, J. Qu, Ye Zhang, X. Che, Yu Cheng, Yibo Fan, Simeng Zhang, Di Na, Yunpeng Liu, X. Qu (2017)
Gastric cancer‐derived exosomes promote peritoneal metastasis by destroying the mesothelial barrierFEBS Letters, 591
Joshua Hood, R. San, S. Wickline (2011)
Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis.Cancer research, 71 11
G. Siravegna, S. Marsoni, S. Siena, A. Bardelli (2017)
Integrating liquid biopsies into the management of cancerNature Reviews Clinical Oncology, 14
Hua-Chuan Zheng (2017)
The molecular mechanisms of chemoresistance in cancersOncotarget, 8
H. Valadi, K. Ekström, A. Bossios, M. Sjöstrand, James Lee, J. Lötvall (2007)
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsNature Cell Biology, 9
A. Janowska-Wieczorek, M. Wysoczynski, J. Kijowski, L. Marquez-Curtis, B. Machalinski, J. Ratajczak, M. Ratajczak (2005)
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancerInternational Journal of Cancer, 113
M. Szajnik, M. Czystowska, M. Szczepański, M. Mandapathil, T. Whiteside (2010)
Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)PLoS ONE, 5
A. Marleau, C. Chen, J. Joyce, R. Tullis (2012)
Exosome removal as a therapeutic adjuvant in cancerJournal of Translational Medicine, 10
J Skog, T Würdinger, S Rijn, DH Meijer, L Gainche, M Sena-Esteves (2008)
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkersNat Cell Biol, 10
L. Lugini, S. Cecchetti, V. Huber, F. Luciani, G. Macchia, F. Spadaro, L. Paris, Laura Abalsamo, M. Colone, A. Molinari, F. Podo, L. Rivoltini, C. Ramoni, S. Fais (2012)
Immune Surveillance Properties of Human NK Cell-Derived ExosomesThe Journal of Immunology, 189
Xiance Jin, Yanfan Chen, Hanbin Chen, Shaoran Fei, Didi Chen, Xiaona Cai, Linger Liu, B. Lin, H. Su, Li-hao Zhao, M. Su, Huanle Pan, Lanxiao Shen, D. Xie, C. Xie (2017)
Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non–Small Cell Lung Cancer Using Next-Generation SequencingClinical Cancer Research, 23
Changjin Huang, D. Quinn, Y. Sadovsky, Subra Suresh, Subra Suresh, K. Hsia (2017)
Formation and size distribution of self-assembled vesiclesProceedings of the National Academy of Sciences of the United States of America, 114
J. Webber, R. Steadman, M. Mason, Z. Tabi, A. Clayton (2010)
Cancer exosomes trigger fibroblast to myofibroblast differentiation.Cancer research, 70 23
F. Slack, J. Weidhaas (2008)
MicroRNA in cancer prognosis.The New England journal of medicine, 359 25
N. Tominaga, N. Kosaka, M. Ono, T. Katsuda, Y. Yoshioka, K. Tamura, J. Lötvall, H. Nakagama, T. Ochiya (2015)
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrierNature Communications, 6
R. Valenti, V. Huber, P. Filipazzi, L. Pilla, Gloria Sovena, A. Villa, A. Corbelli, S. Fais, G. Parmiani, L. Rivoltini (2006)
Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes.Cancer research, 66 18
W. Merritt, Yvonne Lin, Liz Han, Aparna Kamat, W. Spannuth, R. Schmandt, D. Urbauer, L. Pennacchio, Jan-Fang Cheng, A. Nick, M. Deavers, A. Mourad-Zeidan, Hua Wang, P. Mueller, M. Lenburg, J. Gray, S. Mok, M. Birrer, G. Lopez-Berestein, R. Coleman, M. Bar‐eli, A. Sood (2008)
Dicer, Drosha, and outcomes in patients with ovarian cancer.The New England journal of medicine, 359 25
J. Pitt, M. Charrier, S. Viaud, F. André, B. Besse, N. Chaput, L. Zitvogel (2014)
Dendritic Cell–Derived Exosomes as Immunotherapies in the Fight against CancerThe Journal of Immunology, 193
Hongyu Liu, Ling Chen, Yaojun Peng, Songyan Yu, Jialin Liu, Liangliang Wu, Lijun Zhang, Qiyan Wu, Xin Chang, Xinguang Yu, Tianyi Liu (2017)
Dendritic cells loaded with tumor derived exosomes for cancer immunotherapyOncotarget, 9
L. Möhrmann, L. Möhrmann, Helen Huang, D. Hong, A. Tsimberidou, S. Fu, S. Piha-Paul, V. Subbiah, D. Karp, A. Naing, A. Krug, D. Enderle, T. Priewasser, M. Noerholm, E. Eitan, Christine Coticchia, George. Stoll, Lisa Jordan, C. Eng, E. Kopetz, J. Skog, F. Meric-Bernstam, F. Janku (2017)
Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced CancersClinical Cancer Research, 24
Kenichiro Koga, Kotaro Matsumoto, T. Akiyoshi, M. Kubo, N. Yamanaka, Akira Tasaki, H. Nakashima, Masafumi Nakamura, S. Kuroki, Masao Tanaka, M. Katano (2005)
Purification, characterization and biological significance of tumor-derived exosomes.Anticancer research, 25 6A
Jun Lu, Jun Li, Shuo Liu, Teng Wang, Alessandro Ianni, E. Bober, T. Braun, R. Xiang, S. Yue (2017)
Exosomal tetraspanins mediate cancer metastasis by altering host microenvironmentOncotarget, 8
J. Deun, P. Mestdagh, P. Agostinis, Özden Akay, Sushma Anand, J. Anckaert, Zoraida Martinez, Tine Baetens, Els Beghein, Laurence Bertier, G. Berx, J. Boere, Stephanie Boukouris, Michel Bremer, Dominik Buschmann, James Byrd, Clara Casert, Lesley Cheng, A. Cmoch, D. Daveloose, E. Smedt, Ş. Demirsoy, V. Depoorter, Bert Dhondt, Tom Driedonks, A. Dudek, Abdou Elsharawy, I. Floris, Andrew Foers, Kathrin Gärtner, A. Garg, Edward Geeurickx, J. Gettemans, F. Ghazavi, B. Giebel, T. Kormelink, Grace Hancock, H. Helsmoortel, A. Hill, V. Hyenne, Hina Kalra, David Kim, J. Kowal, S. Kraemer, P. Leidinger, C. Leonelli, Yaxuan Liang, L. Lippens, Shu Liu, Alessandra Cicero, Shaun Martin, S. Mathivanan, P. Mathiyalagan, Tamás Matusek, G. Milani, M. Monguió-Tortajada, Liselot Mus, D. Muth, A. Németh, E. Hoen, L. O’Driscoll, Roberta Palmulli, M. Pfaffl, Bjarke Primdal-Bengtson, E. Romano, Quentin Rousseau, S. Sahoo, Natália Sampaio, Monisha Samuel, Benjamin Scicluna, B. Soen, Anneleen Steels, J. Swinnen, M. Takatalo, S. Thaminy, C. Théry, Joeri Tulkens, Isabel Audenhove, S. Grein, Alan Goethem, M. Herwijnen, Guillaume Niel, N. Roy, A. Vliet, N. Vandamme, Suzanne Vanhauwaert, Glenn Vergauwen, F. Verweij, Annelynn Wallaert, M. Wauben, K. Witwer, Marijke Zonneveld, O. Wever, J. Vandesompele, A. Hendrix (2017)
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle researchNature Methods, 14
E. Donnarumma, D. Fiore, M. Nappa, G. Roscigno, Assunta Adamo, M. Iaboni, V. Russo, Alessandra Affinito, Ilaria Puoti, C. Quintavalle, A. Rienzo, S. Piscuoglio, Renato Thomas, G. Condorelli (2017)
Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancerOncotarget, 8
Hamid Cheshmi (2011)
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkersNew Cellular and Molecular Biotechnology Journal, 1
Shin-ichiro Ohno, M. Takanashi, K. Sudo, Shinobu Ueda, A. Ishikawa, N. Matsuyama, Koji Fujita, Takayuki Mizutani, T. Ohgi, T. Ochiya, N. Gotoh, M. Kuroda (2013)
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells.Molecular therapy : the journal of the American Society of Gene Therapy, 21 1
L. Pascucci, V. Coccè, A. Bonomi, Diletta Ami, P. Ceccarelli, E. Ciusani, L. Viganò, A. Locatelli, F. Sisto, S. Doglia, E. Parati, M. Bernardo, M. Muraca, G. Alessandri, G. Bondiolotti, A. Pessina (2014)
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.Journal of controlled release : official journal of the Controlled Release Society, 192
B. Toth, R. Nieuwland, S. Liebhardt, N. Ditsch, K. Steinig, P. Stieber, A. Rank, P. Göhring, C. Thaler, K. Friese, I. Bauerfeind (2008)
Circulating microparticles in breast cancer patients: a comparative analysis with established biomarkers.Anticancer research, 28 2A
Snyder Hw, Balint Jp, J. Fr (1989)
Modulation of immunity in patients with autoimmune disease and cancer treated by extracorporeal immunoadsorption with PROSORBA columns.Seminars in hematology, 26 2 Suppl 1
S. Paget (1989)
The distribution of secondary growths in cancer of the breast. 1889.Cancer metastasis reviews, 8 2
B. Costa-Silva, Nicole Aiello, A. Ocean, Swarnima Singh, Haiying Zhang, B. Thakur, A. Becker, Ayuko Hoshino, M. Mark, H. Molina, J. Xiang, Tuo Zhang, T. Theilen, G. García‐Santos, Caitlin Williams, Yonathan Ararso, Yujie Huang, G. Rodrigues, Tang-Long Shen, K. Labori, I. Lothe, E. Kure, Jonathan Hernandez, A. Doussot, Saya Ebbesen, P. Grandgenett, M. Hollingsworth, Maneesh Jain, K. Mallya, S. Batra, W. Jarnagin, R. Schwartz, Irina Matei, H. Peinado, B. Stanger, J. Bromberg, D. Lyden (2015)
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liverNature Cell Biology, 17
Xiaoyu Xiang, A. Poliakov, Cunren Liu, Yuelong Liu, Zhong‐bin Deng, Jianhua Wang, Ziqiang Cheng, Spandan Shah, Guihua Wang, Liming Zhang, W. Grizzle, J. Mobley, Huang-Ge Zhang (2009)
Induction of myeloid‐derived suppressor cells by tumor exosomesInternational Journal of Cancer, 124
K. Shedden, Xuesun Xie, Parthapratim Chandaroy, Young‐Tae Chang, G. Rosania (2003)
Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles.Cancer research, 63 15
S. Ludwig, T. Floros, M. Theodoraki, Chang‐Sook Hong, E. Jackson, S. Lang, T. Whiteside (2017)
Suppression of Lymphocyte Functions by Plasma Exosomes Correlates with Disease Activity in Patients with Head and Neck CancerClinical Cancer Research, 23
Lin Zhang, Siyuan Zhang, Jun Yao, Frank Lowery, Qingling Zhang, Wen-Chien Huang, Ping Li, Min Li, Xiao Wang, Chenyu Zhang, Hai Wang, K. Ellis, Mujeeb Cheerathodi, J. McCarty, D. Palmieri, J. Saunus, S. Lakhani, Suyun Huang, A. Sahin, K. Aldape, P. Steeg, Dihua Yu (2015)
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowthNature, 527
S. Kamerkar, Valerie LeBleu, H. Sugimoto, Sujuan Yang, C. Ruivo, S. Melo, S. Melo, J. Lee, R. Kalluri (2017)
Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic CancerNature, 546
Haiyang Zhang, T. Deng, Rui Liu, M. Bai, Li-kun Zhou, Xia Wang, Shuang Li, Xinyi Wang, Haiou Yang, Jialu Li, T. Ning, Dingzhi Huang, Hong-li Li, Le Zhang, G. Ying, Y. Ba (2017)
Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasisNature Communications, 8
K. Al-Nedawi, B. Meehan, J. Micallef, V. Lhoták, L. May, A. Guha, J. Rak (2008)
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cellsNature Cell Biology, 10
S. Lange, M. Gallagher, Sharad Kholia, Uchini Kosgodage, M. Hristova, J. Hardy, J. Inal (2017)
Peptidylarginine Deiminases—Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?International Journal of Molecular Sciences, 18
R. Szatanek, M. Baj-Krzyworzeka, J. Zimoch, M. Lekka, M. Siedlar, J. Baran (2017)
The Methods of Choice for Extracellular Vesicles (EVs) CharacterizationInternational Journal of Molecular Sciences, 18
F. André, N. Schartz, M. Movassagh, C. Flament, P. Pautier, P. Morice, C. Pomel, C. Lhommé, B. Escudier, T. Chevalier, T. Tursz, S. Amigorena, G. Raposo, E. Angevin, L. Zitvogel (2002)
Malignant effusions and immunogenic tumour-derived exosomesThe Lancet, 360
M. Plebanek, N. Angeloni, E. Vinokour, Jia Li, Anna Henkin, D. Martinez-Marin, S. Filleur, Reshma Bhowmick, J. Henkin, S. Miller, I. Ifergan, Yesung Lee, I. Osman, C. Thaxton, O. Volpert (2017)
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic nicheNature Communications, 8
J. Kowal, Guillaume Arras, Marina Colombo, M. Jouve, Jakob Morath, Bjarke Primdal-Bengtson, F. Dingli, D. Loew, M. Tkach, C. Théry (2016)
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypesProceedings of the National Academy of Sciences, 113
G. Patel, M. Khan, A. Bhardwaj, S. Srivastava, H. Zubair, Mary Patton, Seema Singh, M. Khushman, A. Singh (2017)
Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCKBritish Journal of Cancer, 116
Yanhua Tian, Suping Li, Jian Song, T. Ji, Motao Zhu, G. Anderson, Jingyan Wei, Guangjun Nie (2014)
A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy.Biomaterials, 35 7
Liang Gao, Lin Wang, Tong Dai, Ke Jin, Zhengkui Zhang, Shuai Wang, Feng Xie, Pengfei Fang, Bing Yang, Huizhe Huang, H. Dam, Fangfang Zhou, Long Zhang (2018)
Tumor-derived exosomes antagonize innate antiviral immunityNature Immunology, 19
P. Wolf (1967)
The Nature and Significance of Platelet Products in Human PlasmaBritish Journal of Haematology, 13
Dongmei Sun, Xiaoying Zhuang, Shuangqin Zhang, Zhong‐bin Deng, W. Grizzle, Donald Miller, Huang-Ge Zhang (2013)
Exosomes are endogenous nanoparticles that can deliver biological information between cells.Advanced drug delivery reviews, 65 3
MET Tesselaar, FPHTM Romijn, IK Linden, FA Prins, RM Bertina, S Osanto (2007)
Microparticle-associated tissue factor activity: a link between cancer and thrombosis?J Thromb Haemost JTH, 5
GK Patel, MA Khan, A Bhardwaj, SK Srivastava, H Zubair, MC Patton (2017)
Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzymeDCK Br J Cancer, 116
Aman Sharma (2018)
Role of stem cell derived exosomes in tumor biologyInternational Journal of Cancer, 142
Exosomes are microvesicles released by cells in both physiological and pathological situations. They are surrounded by a lipid bilayer with proteins derived from the origin cell, and contain a variety of molecules, such as nucleic acids. They represent an emerging mechanism of intercellular communication, and they play an important role in the pathogenesis of cancer, stimulating proliferation and aggressiveness of cancer cells, inducing a microenvironment favorable to tumor development and controlling immune responses. Because of the growing understanding of the potential implications of extracellular vesicles in the development of malignancies, research on exosomes, and its role as a diagnostic and therapeutic tool, constitutes nowadays a very exciting and promising field.
Cancer Microenvironment – Springer Journals
Published: May 3, 2018
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