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K. Burman, J. Earll, M. Johnson, L. Wartofsky (1974)
Clinical observations on the solitary autonomous thyroid nodule.Archives of internal medicine, 134 5
B. Nygaard, L. Hegedüs, K. Nielsen, P. Ulriksen, J. Hansen (1999)
Long‐term effect of radioactive iodine on thyroid function and size in patients with solitary autonomously functioning toxic thyroid nodulesClinical Endocrinology, 50
Wei Zhang, Zhuo-Qun Huang, Weilong Lin, Shi-Hong Yang (2017)
RE: Novel Application of Quantitative Single-Photon Emission Computed Tomography/Computed Tomography to Predict Early Response to Methimazole in Graves' DiseaseKorean Journal of Radiology, 19
Hyunjong Lee, J. Kim, Yeon-Koo Kang, J. Moon, Y. So, Won Lee (2016)
Quantitative single-photon emission computed tomography/computed tomography for technetium pertechnetate thyroid uptake measurementMedicine, 95
R. Bahn, Henry Burch, David Cooper, J. Garber, M. Greenlee, I. Klein, Peter Laurberg, I. McDougall, Victor Montori, S. Rivkees, Douglas Ross, Julie Sosa, Marius Stan (2011)
Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists.Thyroid : official journal of the American Thyroid Association, 21 6
Johannes Meller, W. Becker (2002)
The continuing importance of thyroid scintigraphy in the era of high-resolution ultrasoundEuropean Journal of Nuclear Medicine and Molecular Imaging, 29
H. Higgins, D. Ball, S. Eastham (1973)
20-Min 99mTc thyroid uptake: a simplified method using the gamma camera.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 14 12
N. Carnell, WILLIAM Valente (1998)
Thyroid nodules in Graves' disease: classification, characterization, and response to treatment.Thyroid : official journal of the American Thyroid Association, 8 8
D. Ross (1991)
Evaluation of the thyroid nodule.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 32 11
A. Kang, C. Grant, G. Thompson, J. Heerden (2002)
Current treatment of nodular goiter with hyperthyroidism (Plummer's disease): surgery versus radioiodine.Surgery, 132 6
P. Ritt, H. Vija, J. Hornegger, T. Kuwert (2011)
Absolute quantification in SPECTEuropean Journal of Nuclear Medicine and Molecular Imaging, 38
L. Hegedüs (2004)
The Thyroid NoduleThe New England Journal of Medicine, 351
Won-Woo Lee, Boyoung Lee, Sung Kim, Jungsun Jin, D. Moon, Heuiran Lee (2003)
Kinetics of iodide uptake and efflux in various human thyroid cancer cells by expressing sodium iodide symporter gene via a recombinant adenovirus.Oncology reports, 10 4
B. Haugen, E. Alexander, K. Bible, Gerard Doherty, S. Mandel, Y. Nikiforov, F. Pacini, G. Randolph, A. Sawka, M. Schlumberger, K. Schuff, S. Sherman, J. Sosa, D. Steward, R. Tuttle, L. Wartofsky (2009)
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.Thyroid : official journal of the American Thyroid Association, 26 1
L Hegedus (2004)
Clinical practice. The thyroid noduleN Engl J Med, 351
E. Mazzaferri (1993)
Management of a solitary thyroid nodule.The New England journal of medicine, 328 8
H. Kim, Ji-In Bang, Ji-Young Kim, J. Moon, Y. So, Won Lee (2017)
Novel Application of Quantitative Single-Photon Emission Computed Tomography/Computed Tomography to Predict Early Response to Methimazole in Graves' DiseaseKorean Journal of Radiology, 18
J. Shimmins, W. Alexander, D. Mclarty, J. Robertson, D. Sloane (1971)
99mTc-pertechnetate for measuring thyroid suppressibility.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 12 2
Z. Kusic, D. Becker, E. Saenger, P. Paras, Peter Gartside, Terry Wessler, Š. Spaventi (1990)
Comparison of technetium-99m and iodine-123 imaging of thyroid nodules: correlation with pathologic findings.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 31 4
A. Goolden, H. Glass, E. Williams (1971)
Use of”Tcm for the Routine Assessment of Thyroid FunctionBritish Medical Journal, 4
H. Gharib, E. Papini (2007)
Thyroid nodules: clinical importance, assessment, and treatment.Endocrinology and metabolism clinics of North America, 36 3
Ji-Young Kim, Ji Kim, J. Moon, K. Kim, T. Oh, Dong-Hwa Lee, Y. So, Won Lee (2018)
Utility of Quantitative Parameters from Single-Photon Emission Computed Tomography/Computed Tomography in Patients with Destructive ThyroiditisKorean Journal of Radiology, 19
D. Cooper, Gerard Doherty, B. Haugen, R. Kloos, Stephanie Lee, S. Mandel, E. Mazzaferri, B. Mciver, F. Pacini, M. Schlumberger, S. Sherman, D. Steward, R. Tuttle (2009)
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.Thyroid : official journal of the American Thyroid Association, 19 11
D. Bailey, K. Willowson (2013)
An Evidence-Based Review of Quantitative SPECT Imaging and Potential Clinical ApplicationsThe Journal of Nuclear Medicine, 54
Planar scintigraphy using Tc-99m pertechnetate is useful for snapshot evaluation of hot thyroid nodules, which are pathologically follicular adenoma and seldom, if ever, malignant. The autonomy of the hot nodules has been demonstrated by the presence of thyroid-stimulating hormone-dependent extra-nodular thyroid tissue besides the hot nodules. Here, we present two cases of hot thyroid nodules in patients who underwent quantitative single-photon emission computed tomography/computed tomography (SPECT/CT). In addition to the nodules, contralateral normal thyroid parenchyma was evaluated based on standardized uptake values. One patient had a traditional follicular adenoma suppressing other thyroid tissue, whereas the other patient seemed to have a nodule erupting from underlying hyperfunctioning, not suppressed, thyroid tissue. This novel approach using quantitative SPECT/CT unveils a new pathology of hot thyroid nodule that does not suppress, but coincides with hyperfunctioning thyroid tissue.
Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Nov 3, 2018
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