Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Epigenetic Changes in Carcinogenesis of Gallbladder

Epigenetic Changes in Carcinogenesis of Gallbladder Abstract Gallbladder cancer (GBC) is a lethal and a common malignancy affecting mostly females. There are restricted high incidence pockets across the world and in northern India highest incidence of GBC is reported from the Gangetic belt. The etiology of this disease remains largely unknown though several risk factors have been stated. The genetic aberrations in GBC involving mutations in tumor suppressor genes and oncogenes have been reported in literature. However, there is scarcity of data regarding epigenetic changes that may also be involved in gallbladder carcinogenesis. This review attempts to summarize our current understanding of the epigenetic changes in GBC. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Indian Journal of Surgical Oncology Springer Journals

Epigenetic Changes in Carcinogenesis of Gallbladder

Download PDF
6 pages

Loading next page...
 
/lp/springer-journals/epigenetic-changes-in-carcinogenesis-of-gallbladder-J1T3ccyW1M
Publisher
Springer Journals
Copyright
2013 Indian Association of Surgical Oncology
ISSN
0975-7651
eISSN
0976-6952
DOI
10.1007/s13193-013-0240-0
Publisher site
See Article on Publisher Site

Abstract

Abstract Gallbladder cancer (GBC) is a lethal and a common malignancy affecting mostly females. There are restricted high incidence pockets across the world and in northern India highest incidence of GBC is reported from the Gangetic belt. The etiology of this disease remains largely unknown though several risk factors have been stated. The genetic aberrations in GBC involving mutations in tumor suppressor genes and oncogenes have been reported in literature. However, there is scarcity of data regarding epigenetic changes that may also be involved in gallbladder carcinogenesis. This review attempts to summarize our current understanding of the epigenetic changes in GBC.

Journal

Indian Journal of Surgical Oncology – Springer Journals

Published: Dec 1, 2013

Keywords: surgical oncology; oncology; surgery

References

  • What causes cancer gallbladder? A review
    P Chaurasia, MK Thakur, HS Shukla
  • Geographic pathology revisited: development of an atlas of cancer in India
    A Nandakumar, PC Gupta, P Gangadharn, RN Visweswara, DM Parkin
  • Consolidated report of the Population Based Cancer Registries 1990–96
    citation_title=Consolidated report of the Population Based Cancer Registries
  • Three year report of the Population Based Cancer Registries 2006–2008
    citation_title=Three year report of the Population Based Cancer Registries
  • Epidemiology of gallbladder disease: cholelithiasis and cancer
    LM Stintom, EA Shaffer
  • Trends in incidence of gallbladder cancer—Indian scenario.
    Murthy NS, Rajaram D, Gautham MS
  • Clinical translation of angiogenesis inhibitors
    R Kerbel, J Folkman
  • Gallbladder carcinoma: radiologic-pathologic correlation
    AD Levy, LA Murakata, CA Rohrmassn
  • Number and size of stones in patients with asymptomatic and symptomatic gallstones and gallbladder carcinoma: a prospective study of 592 cases
    A Csendes, M Becerra, J Rojas, E Medina
  • Epidemiologic aspects of gallbladder cancer: a case–control study of the SEARCH Program of the International Agency for Research on Cancer
    WA Zatonski, AB Lowenfels, P Boyle, P Maisonneuve, B Mesquita HB
  • Contribution of silent gallstones in gallbladder cancer
    M Tewari
  • Cancer mortality in chronic typhoid and paratyphoid carriers
    CP Caygill, MJ Hill, M Braddick, JC Sharp
  • Risk factors for gallbladder cancer. An international collaborative case–control study
    BL Storm, RD Soloway, JL Rios-Dalenz
  • Salmonella typhi and gallbladder cancer: report from an endemic region
    M Tewari, RR Mishra, HS Shukla
  • Helicobacter pylori and pathogenesis of gallbladder cancer
    RR Mishra, M Tewari, HS Shukla
  • Helicobacter pylori and the risk of benign and malignant biliary tract disease
    M Bulajic, P Maisonneuve, W Scheider-Brachert
  • Discovery of Helicobacter pylori in gallbladder
    HS Shukla, M Tewari
  • Gallbladder polyps: epidemiology, natural history and management
    RP Myers, EA Shaffer, P Beck
  • Correlates between vegetable consumption and gallbladder cancer
    A Rai, SC Mohapatra, HS Shukla
  • Role of fruit consumption in gall bladder cancer
    A Rai, SC Mohapatra, HS Shukla
  • Obesity and the risk of gallbladder cancer: a meta-analysis
    SC Larsson, A Wolk
  • Abdominal obesity, weight gain during adulthood and risk of liver and biliary tract cancer in a European cohort
    S Schlesinger, K Aleksandrova, T Pischon, V Fedirko, M Jenab
  • Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation
    G Andreotti, E Liu, YT Gao, M Safaeian, A Rashid, MC Shen
  • Changes in the concentrations of chlornitrofen (CNP) and CNP-amino in river and faucet water in Niigata, Japan
    Y Adachi
  • Ecological correlation studies on standardized incidence ratios of malignant neoplasms contracted from different sources of drinking water supply
    M Yamamoto, K Endoh, H Nakadaira
  • Epidemiological factors of cancer in California
    EM Moran
  • An objective assessment of demography of gallbladder cancer
    JR Kumar, M Tewari, A Rai, R Sinha, SC Mohapatra, HS Shukla
  • Cholecystectomy in patients with asymptomatic gallstones to prevent gall bladder cancer—the case against
    VK Kapoor
  • Cholecystokinin and gastrin receptors targeting in gastrointestinal cancer
    R Rai, V Chandra, M Tewari, M Kumar, HS Shukla
  • Expression pattern of tumor endothelial marker 8 protein in gallbladder carcinomas
    SK Maurya, M Tewari, MK Thakur, HS Shukla
  • Stage dependent expression of MUC1 glycoprotein in gallbladder carcinoma
    SK Maurya, M Tewari, MK Thakur, M Kumar, HS Shukla
  • Genetic aberrations in gallbladder cancer
    SK Maurya, M Tewari, RR Mishra, HS Shukla
  • p53: its alteration and gallbladder cancer
    R Rai, M Tewari, M Kumar, AK Singh, HS Shukla
  • Preliminary study of p53 and c-erbB-2 expression in gallbladder cancer in Indian patients manuscript id: 8962091628764582
    A Chaube, M Tewari, RS Garbyal, U Singh, HS Shukla
  • The frequency of live bacteria in gallstones
    P Hazarah, KTH Oahn, M Tewari, AK Pandey, K Kumar, TM Mohapatra, HS Shukla
  • Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation
    Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher B
  • Environmental toxicants, epigenetics, and cancer
    IP Pogribny, I Rusyn
  • DNA methylation alterations in response to pesticide exposure in vitro
    X Zhang, AD Wallace, P Du, WA Kibbe, N Jafari, H Xie
  • Environmental epigenetics in metal exposure
    R Martinez-Zamudio, HC Ha
  • HOX gene methylation status analysis in patients with hereditary breast cancer
    B Pilato, R Pinto, S Summa, R Lambo, A Paradiso, S Tommasi
  • Aberrant promoter CpG methylation and its translational applications in breast cancer
    TX Xiang, Y Yuan, LL Li, ZH Wang, LY Dan, Y Chen, GS Ren, Q Tao
  • WT1 CpG islands methylation in human lung cancer: a pilot study
    P Bruno, G Gentile, R Mancini, C Vitis, MC Esposito, D Scozzi
  • DNA methylation changes in prostate cancer
    W Goering, M Kloth, WA Schulz
  • Epigenetics alterations in preneoplastic and neoplastic lesions of the cervix
    K Saavedra KF, P Brebi PS, JC Roa
  • Inflammation, DNA methylation and colitis-associated cancer
    L Hartnett, LJ Egan
  • Epigenetic changes in colorectal cancer
    Y Jia, M Guo
  • XAF1 is frequently methylated in human esophageal cancer
    XY Chen, QY He, MZ Guo
  • Stomach—genetic and epigenetic alterations of preneoplastic and neoplastic lesions
    S David, SJ Meltzer
  • Molecular changes in the multistage pathogenesis of head and neck cancer
    BJ Park, SI Chiosea, JR Grandis
  • Association of secondhand smoke exposures with DNA methylation in bladder carcinomas
    CS Wilhelm-Benartzi, BC Christensen, DC Koestler, E Andres Houseman, AR Schned, MR Karagas
  • Epigenetic changes in osteosarcoma
    J Cui, W Wang, Z Li, Z Zhang, B Wu, L Zeng
  • Seed in soil, with an epigenetic view
    HJ Lin, T Zuo, JR Chao, Z Peng, LK Asamoto, SS Yamashita, TH Huang
  • Epigenetic aberrations and cancer
    M Ducasse, MA Brown
  • Epigenetic changes of DNA repair genes in cancer
    C Lahtz, GP Pfeifer
  • DNA methylation, imprinting and cancer
    C Plass, PD Soloway
  • Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
    Y Zhang, HH Ng, H Erdjument-Bromage, P Tempst, A Bird, D Reinberg
  • The many roles of histone deacetylases in development and physiology: implications for disease and therapy
    M Haberland, RL Montgomery, EN Olson
  • MiRNAs, epigenetics, cancer
    A Rouhi, DL Mager, RK Humphries, F Kuchenbauer
  • Epigenetic reprogramming in mammalian development
    W Reik, W Dean, J Walter
  • Genetic alterations in preneoplastic and neoplastic injuries of the gallbladder. [Article in Spanish]
    J Castillo, P García, JC Roa
  • Progression of gene hypermethylation in gallstone disease leading to gallbladder cancer
    MG House, II Wistuba, P Argani
  • Promoter methylation profile in preneoplastic and neoplastic gallbladder lesions
    P Garcia, C Manterola, JC Araya, M Villaseca, P Guzman, A Sanhueza
  • Promoter methylation profile in gallbladder cancer
    JC Roa, L Anabalon, I Roa, A Melo, JC Araya, O Tapia
  • Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis
    T Takahashi, N Shivapurkar, E Riquelme, H Shigematsu, J Reddy, M Suzuki
  • Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells
    K Matsuda, H Maruyama, F Guo
  • Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers
    K Miyamoto, K Asada, T Fukutomi
  • Hypomethylation of the protein gene product 9.5 promoter region in gallbladder cancer and its relationship with clinicopathological features
    YM Lee, JY Lee, MJ Kim, HI Bae, JY Park, SG Kim, DS Kim
  • Hypermethylation of the Ras association domain family 1A (RASSF1A) gene in gallbladder cancer
    SK Kee, JY Lee, MJ Kim, SM Lee, YW Jung, YJ Kim
  • Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma
    E Riquelme, M Tang, S Baez, A Diaz, M Pruyas, II Wistuba, A Corvalan
  • DNA promoter methylation as a diagnostic and therapeutic biomarker in gallbladder cancer
    P Letelier, P Brebi, O Tapia, JC Roa