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Enhanced heinz body formation, cell lysis and anaemia in a Koala (Phascolarctos cinereus)

Enhanced heinz body formation, cell lysis and anaemia in a Koala (Phascolarctos cinereus) Heinz body-mediated lysis of erythrocytes was detected in a free-living koala. The anaemia was markedly regenerative and characterised by ghost cells and numerous large Heinz bodies on peripheral blood films. Endogenous and exogenous causes of increased Heinz body formation were considered. The fact that Heinz bodies are also present in the blood of healthy koalas suggests that this species may be particularly susceptible to oxidant damage of haemoglobin in a manner similar to that occurring in the domestic cat. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

Enhanced heinz body formation, cell lysis and anaemia in a Koala (Phascolarctos cinereus)

Spencer, A.; Canfield, P.
Comparative Clinical Pathology , Volume 4 (2) – Sep 8, 2004
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Publisher
Springer Journals
Copyright
Copyright © 1994 by Springer-Verlag London Limited
Subject
Medicine & Public Health; Pathology; Hematology; Oncology
eISSN
1433-2973
DOI
10.1007/BF00368278
Publisher site
See Article on Publisher Site

Abstract

Heinz body-mediated lysis of erythrocytes was detected in a free-living koala. The anaemia was markedly regenerative and characterised by ghost cells and numerous large Heinz bodies on peripheral blood films. Endogenous and exogenous causes of increased Heinz body formation were considered. The fact that Heinz bodies are also present in the blood of healthy koalas suggests that this species may be particularly susceptible to oxidant damage of haemoglobin in a manner similar to that occurring in the domestic cat.

Journal

Comparative Clinical Pathology – Springer Journals

Published: Sep 8, 2004

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