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Endometrial Stromal Sarcoma

Endometrial Stromal Sarcoma Uterine sarcomas comprise 2–3% of all uterine malignancies. Tumors in this category are, in order of decreasing incidence, carcinosarcoma, leiomyosarcoma, endometrial stromal sarcoma, and adenosarcoma. Endometrial stromal sarcomas are divided into low- and high-grade according to tumor cell morphology and mitotic rate. Low-grade tumors are characterized by a slow growth pattern, presence of estrogen and/or progesterone receptors, and an indolent clinical course with late recurrences. Despite this indolent course, 37–60% of patients with early-stage disease experience recurrent disease. High-grade stromal sarcomas, on the other hand, exhibit more aggressive biological behavior and poor outcome. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cancer Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2004 by Adis Data Information BV
Subject
Pharmacy; Pharmacy
ISSN
1175-6357
DOI
10.2165/00024669-200403010-00002
Publisher site
See Article on Publisher Site

Abstract

Uterine sarcomas comprise 2–3% of all uterine malignancies. Tumors in this category are, in order of decreasing incidence, carcinosarcoma, leiomyosarcoma, endometrial stromal sarcoma, and adenosarcoma. Endometrial stromal sarcomas are divided into low- and high-grade according to tumor cell morphology and mitotic rate. Low-grade tumors are characterized by a slow growth pattern, presence of estrogen and/or progesterone receptors, and an indolent clinical course with late recurrences. Despite this indolent course, 37–60% of patients with early-stage disease experience recurrent disease. High-grade stromal sarcomas, on the other hand, exhibit more aggressive biological behavior and poor outcome.

Journal

American Journal of CancerSpringer Journals

Published: Aug 10, 2012

References