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Embedding of Biological Regulatory Networks and Property Preservation

Embedding of Biological Regulatory Networks and Property Preservation In the course of understanding biological regulatory networks (BRN), scientists usually start by studying small BRNs that they believe to be of particular importance to represent a biological function, and then, embed them in a larger network. Such a reduction can lead to neglect relevant regulations and to study a network whose properties can be very different from the properties of this network viewed as a part of the whole. In this paper we study, from a logical point of view, on which conditions concerning both networks, properties can be inherited by BRNs from sub-BRNs. We give some conditions on the nature of the network embeddings ensuring that dynamic properties on the embedded sub-BRNs are preserved at the level of the whole BRN. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mathematics in Computer Science Springer Journals

Embedding of Biological Regulatory Networks and Property Preservation

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References (45)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer Basel AG
Subject
Mathematics; Mathematics, general; Computer Science, general
ISSN
1661-8270
eISSN
1661-8289
DOI
10.1007/s11786-011-0092-3
Publisher site
See Article on Publisher Site

Abstract

In the course of understanding biological regulatory networks (BRN), scientists usually start by studying small BRNs that they believe to be of particular importance to represent a biological function, and then, embed them in a larger network. Such a reduction can lead to neglect relevant regulations and to study a network whose properties can be very different from the properties of this network viewed as a part of the whole. In this paper we study, from a logical point of view, on which conditions concerning both networks, properties can be inherited by BRNs from sub-BRNs. We give some conditions on the nature of the network embeddings ensuring that dynamic properties on the embedded sub-BRNs are preserved at the level of the whole BRN.

Journal

Mathematics in Computer ScienceSpringer Journals

Published: Nov 27, 2011

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