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G. Prasanna, C. Hulet, D. Desai, R. Krishnamoorthy, S. Narayan, A. Brun, A. Suburo, T. Yorio (2005)
Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma.Pharmacological research, 51 1
T. Ota, Hiroshi Murata, Ei-ichiro Sugimoto, M. Aihara, M. Araie (2005)
Prostaglandin analogues and mouse intraocular pressure: effects of tafluprost, latanoprost, travoprost, and unoprostone, considering 24-hour variation.Investigative ophthalmology & visual science, 46 6
I. Surgucheva, B. McMahan, F. Ahmed, S. Tomarev, M. Wax, A. Surguchov (2002)
Synucleins in glaucoma: Implication of γ‐synuclein in glaucomatous alterations in the optic nerveJournal of Neuroscience Research, 68
KD Bojikian, PP Chen, JC Wen (2019)
Optical coherence tomography angiography in glaucomaCurr Opin Ophthalmol, 30
Jui-ling Liu, Y. Ko, C.-Y. Cheng, J. Chou, W. Hsu, J-H Liu, MD Liu (2002)
Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucomaBritish Journal of Ophthalmology, 86
A. Sutton, A. Gilvarry, A. Ropo (2007)
A comparative, placebo-controlled study of prostanoid fluoroprostaglandin-receptor agonists tafluprost and latanoprost in healthy males.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 23 4
G. Rubanyi, M. Polokoff (1994)
Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.Pharmacological reviews, 46 3
H. Quigley, A. Broman (2006)
The number of people with glaucoma worldwide in 2010 and 2020British Journal of Ophthalmology, 90
M. Orme, S. Collins, H. Dakin, S. Kelly, J. Loftus (2010)
Mixed treatment comparison and meta-regression of the efficacy and safety of prostaglandin analogues and comparators for primary open-angle glaucoma and ocular hypertensionCurrent Medical Research and Opinion, 26
Jaewan Choi, M. Kook (2015)
Systemic and Ocular Hemodynamic Risk Factors in GlaucomaBioMed Research International, 2015
N. Kurysheva, E. Maslova, A. Trubilina, A. Fomin, M. Lagutin (2018)
[Pattern visual evoked potentials and their relation to the peripapillary and retrobulbar blood flow in glaucoma].Vestnik oftalmologii, 134 3
S. Moghimi, L. Zangwill, Rafaella Penteado, K. Hasenstab, Elham Ghahari, Huiyuan Hou, Mark Christopher, A. Yarmohammadi, P. Manalastas, Takuhei Shoji, C. Bowd, R. Weinreb (2018)
Macular and Optic Nerve Head Vessel Density and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma.Ophthalmology, 125 11
Y. Decai, Yang Xiaozhe, Zhang Xiaoming, Y. Yujie, Wang Jue, Yu Juan (2021)
A Review of the Influencing Factors of Adolescents' Non-Suicidal Self-Injury, 3
I Lanzl, T Hamacher, K Rosbach (2013)
Preservative-free tafluprost in the treatment of naive patients with glaucoma and ocular hypertensionClin Ophthalmol, 7
Yuejiao Jin, Xiaofei Wang, Liang Zhang, J. Jonas, T. Aung, L. Schmetterer, M. Girard (2018)
Modeling the Origin of the Ocular Pulse and Its Impact on the Optic Nerve Head.Investigative ophthalmology & visual science, 59 10
Yochai Shoshani, A. Harris, M. Shoja, Deepam Rusia, B. Siesky, Y. Arieli, B. Wirostko (2012)
Endothelin and Its Suspected Role in the Pathogenesis and Possible Treatment of GlaucomaCurrent Eye Research, 37
I. Surgucheva, B. McMahan, F. Ahmed, S. Tomarev, M. Wax, A. Surguchov (2002)
Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve.Journal of neuroscience research, 68 1
C. Mayama, K. Ishii, T. Saeki, T. Ota, A. Tomidokoro, M. Araie (2010)
Effects of topical phenylephrine and tafluprost on optic nerve head circulation in monkeys with unilateral experimental glaucoma.Investigative ophthalmology & visual science, 51 8
Liang Liu, Yali Jia, H. Takusagawa, Alex Pechauer, B. Edmunds, Lorinna Lombardi, Ellen Davis, J. Morrison, David Huang (2015)
Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma.JAMA ophthalmology, 133 9
J. Stjernschantz, G. Selén, M. Astin, B. Resul (2000)
Microvascular effects of selective prostaglandin analogues in the eye with special reference to latanoprost and glaucoma treatmentProgress in Retinal and Eye Research, 19
D. Kuerten, M. Fuest, E. Koch, A. Koutsonas, N. Plange (2015)
Retrobulbar Hemodynamics and Visual Field Progression in Normal Tension Glaucoma: A Long-Term Follow-Up StudyBioMed Research International, 2015
M. Hellberg, V. Sallee, Marsha McLaughlin, Naj Sharif, Louis Desantis, T. Dean, P. Zinke (2001)
Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 17 5
N. Kurysheva (2019)
Assessment of the optic nerve head, peripapillary, and macular microcirculation in the newly diagnosed patients with primary open-angle glaucoma treated with topical tafluprost and tafluprost/timolol fixed combinationTaiwan Journal of Ophthalmology, 9
Y. Takagi, T. Nakajima, A. Shimazaki, M. Kageyama, T. Matsugi, Y. Matsumura, B. Gabelt, P. Kaufman, H. Hara (2004)
Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug.Experimental eye research, 78 4
Joshua Shin, Amber Wolf, A. Harris, A. Vercellin, B. Siesky, Lucas Rowe, M. Packles, F. Oddone (2021)
Vascular biomarkers from optical coherence tomography angiography and glaucoma: where do we stand in 2021?Acta Ophthalmologica, 100
M. Sasaoka, T. Taniguchi, M. Shimazawa, N. Ishida, A. Shimazaki, H. Hara (2006)
Intravitreal injection of endothelin-1 caused optic nerve damage following to ocular hypoperfusion in rabbits.Experimental eye research, 83 3
I Ohguro (2010)
Effects of administration of tafluprost on optic nerve head blood flow in patients with normal tension glaucomaGanka, 52
J Ishigaki, S Miyaka, S Harino (2010)
Effect of Tafluprost on choroidal blood flow in glaucomaAtarashii Ganka (J Eye), 27
Ji Kwon, R. Weinreb, L. Zangwill, M. Suh (2021)
Juxtapapillary Deep-Layer Microvasculature Dropout and Retinal Nerve Fiber Layer Thinning in Glaucoma.American journal of ophthalmology
Amália Giannico, Leandro Lima, G. Shaw, H. Russ, T. Froes, F. Montiani-Ferreira (2016)
Effects of prostaglandin analogs on blood flow velocity and resistance in the ophthalmic artery of rabbits.Arquivos brasileiros de oftalmologia, 79 1
N. Izumi, T. Nagaoka, E. Sato, F. Mori, A. Takahashi, Kenji Sogawa, A. Yoshida (2008)
Short-term effects of topical tafluprost on retinal blood flow in cats.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 24 5
Ji Kwon, R. Weinreb, L. Zangwill, M. Suh (2019)
Parapapillary Deep-Layer Microvasculature Dropout and Visual Field Progression in Glaucoma.American journal of ophthalmology, 200
S. Roth, Z. Pietrzyk, A. Crittenden (1994)
The effects of enflurane on ocular blood flow.Journal of ocular pharmacology, 9 3
M. Aihara (2010)
Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertensionClinical Ophthalmology (Auckland, N.Z.), 4
(2010)
Microcirculation in the optic nerve head before and after instillation of tafluprost in healthy humans
P. Stanga, E. Tsamis, A. Papayannis, Francesco Stringa, Tim Cole, A. Jalil (2016)
Swept-Source Optical Coherence Tomography Angio™ (Topcon Corp, Japan): Technology Review.Developments in ophthalmology, 56
D. Seo, S. Ha (2015)
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination EyedropsBioMed Research International, 2015
Yih-Chung Tham, Xiang Li, T. Wong, H. Quigley, T. Aung, Ching-Yu Cheng (2014)
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.Ophthalmology, 121 11
T. Nakajima, T. Matsugi, W. Goto, M. Kageyama, N. Mori, Y. Matsumura, H. Hara (2003)
New fluoroprostaglandin F(2alpha) derivatives with prostanoid FP-receptor agonistic activity as potent ocular-hypotensive agents.Biological & pharmaceutical bulletin, 26 12
J. Jonas, Pascal Weber, Natsuko Nagaoka, K. Ohno-Matsui (2017)
Glaucoma in high myopia and parapapillary delta zonePLoS ONE, 12
G. Holló (2018)
Optical Coherence Tomography Angiography in GlaucomaTurkish Journal of Ophthalmology, 48
Yuto Iida, T. Akagi, Hideo Nakanishi, Hanako Ikeda, S. Morooka, K. Suda, Tomoko Hasegawa, S. Yokota, Munemitsu Yoshikawa, A. Uji, N. Yoshimura (2017)
Retinal Blood Flow Velocity Change in Parafoveal Capillary after Topical Tafluprost Treatment in Eyes with Primary Open-angle GlaucomaScientific Reports, 7
R. Rosenthal, M. Fromm (2011)
Endothelin antagonism as an active principle for glaucoma therapyBritish Journal of Pharmacology, 162
(2010)
Effect of Tafluprost on choroidal blood flow in glaucoma. Atarashii Ganka (J Eye)
Yali Jia, Eric Wei, Xiaogang Wang, Xinbo Zhang, J. Morrison, M. Parikh, Lorinna Lombardi, D. Gattey, R. Armour, B. Edmunds, Martin Kraus, J. Fujimoto, David Huang (2014)
Optical coherence tomography angiography of optic disc perfusion in glaucoma.Ophthalmology, 121 7
H. Kurashima, Hiroshi Watabe, N. Sato, Sanae Abe, N. Ishida, T. Yoshitomi (2010)
Effects of prostaglandin F(2α) analogues on endothelin-1-induced impairment of rabbit ocular blood flow: comparison among tafluprost, travoprost, and latanoprost.Experimental eye research, 91 6
J. Lee, K. Sung, Jin Lee (2016)
Comparison of the Progression of High- and Low-tension Glaucoma as Determined by Two Different CriteriaKorean Journal of Ophthalmology : KJO, 30
Yaru Dong, Hiroshi Watabe, Guanfang Su, H. Ishikawa, N. Sato, T. Yoshitomi (2008)
Relaxing effect and mechanism of tafluprost on isolated rabbit ciliary arteries.Experimental eye research, 87 3
Huiyuan Hou, S. Moghimi, L. Zangwill, Takuhei Shoji, Elham Ghahari, Rafaella Penteado, T. Akagi, P. Manalastas, R. Weinreb (2019)
Macula Vessel Density and Thickness in Early Primary Open-Angle Glaucoma.American journal of ophthalmology, 199
(2015)
Effects on visual field, morphology and microcirculation of optic nerve head following tafluprost treatment for 3 years in patients with glaucoma
C. Kaufmann, L. Bachmann, Y. Robert, M. Thiel (2006)
Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry.Archives of ophthalmology, 124 8
Satoru Tsuda, Yu Yokoyama, Naoki Chiba, Naoko Aizawa, Yukihiro Shiga, Masayuki Yasuda, S. Yokokura, Takaaki Otomo, N. Fuse, T. Nakazawa (2013)
Effect of Topical Tafluprost on Optic Nerve Head Blood Flow in Patients With Myopic Disc TypeJournal of Glaucoma, 22
S. Roth (1992)
The effects of halothane on retinal and choroidal blood flow in cats.Anesthesiology, 76 3
Takuhei Shoji, L. Zangwill, T. Akagi, L. Saunders, A. Yarmohammadi, P. Manalastas, Rafaella Penteado, R. Weinreb (2017)
Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study.American journal of ophthalmology, 182
V. Brücher, J. Storp, N. Eter, M. Alnawaiseh (2019)
Optical coherence tomography angiography-derived flow density: a review of the influencing factorsGraefe's Archive for Clinical and Experimental Ophthalmology, 258
C. Traverso, A. Ropo, M. Papadia, H. Uusitalo (2010)
A phase II study on the duration and stability of the intraocular pressure-lowering effect and tolerability of Tafluprost compared with latanoprost.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 26 1
H. Chen, Chun-Hsiu Liu, Wei-Chi Wu, Hsiao-Jung Tseng, Yung-Sung Lee (2017)
Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes.Investigative ophthalmology & visual science, 58 9
Hannah Weindler, M. Spitzer, M. Schultheiss, R. Kromer (2020)
OCT angiography analysis of retinal vessel density in primary open-angle glaucoma with and without Tafluprost therapyBMC Ophthalmology, 20
Takahiro Akaishi, H. Kurashima, Noriko Odani-Kawabata, N. Ishida, Masatsugu Nakamura (2010)
Effects of repeated administrations of tafluprost, latanoprost, and travoprost on optic nerve head blood flow in conscious normal rabbits.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 26 2
H. Quigley (1996)
Number of people with glaucoma worldwide.British Journal of Ophthalmology, 80
A. Yarmohammadi, L. Zangwill, Alberto Diniz-Filho, M. Suh, Siamak Yousefi, L. Saunders, A. Belghith, P. Manalastas, F. Medeiros, R. Weinreb (2016)
Relationship between Optical Coherence Tomography Angiography Vessel Density and Severity of Visual Field Loss in Glaucoma.Ophthalmology, 123 12
Lingyan Cheng, Yuzhi Ding, Xuanchu Duan, Zhifeng Wu (2017)
Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow-up of glaucomaExperimental and Therapeutic Medicine, 14
T Sugiyama, M Shibata, S Kojima (2011)
Changes in microcirculation in the optic nerve head following topical tafluprost in eyes with primary open-angle glaucomaRinsho Ganka (Jpn J Clin Ophthalmol), 65
Sanae Abe, Hiroshi Watabe, S. Takaseki, M. Aihara, T. Yoshitomi (2013)
The effects of prostaglandin analogues on intracellular Ca2+ in ciliary arteries of wild-type and prostanoid receptor-deficient mice.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 29 1
A. Konstas, Konstadinos Boboridis, Paraskevas Kapis, Konstantinos Marinopoulos, I. Voudouragkaki, Dimitrios Panayiotou, D. Mikropoulos, Eirini Pagkalidou, A. Haidich, A. Katsanos, L. Quaranta (2016)
24-Hour Efficacy and Ocular Surface Health with Preservative-Free Tafluprost Alone and in Conjunction with Preservative-Free Dorzolamide/Timolol Fixed Combination in Open-Angle Glaucoma Patients Insufficiently Controlled with Preserved Latanoprost MonotherapyAdvances in Therapy, 34
S. Biswas, P. Bhattacherjee, C. Paterson (2004)
Prostaglandin E2 receptor subtypes, EP1, EP2, EP3 and EP4 in human and mouse ocular tissues--a comparative immunohistochemical study.Prostaglandins, leukotrienes, and essential fatty acids, 71 5
A. Sutton, P. Gouws, A. Ropo (2008)
Tafluprost, a new potent prostanoid receptor agonist: a dose-response study on pharmacodynamics and tolerability in healthy volunteers.International journal of clinical pharmacology and therapeutics, 46 8
J. Jonas, Y. Wang, L. Dong, S. Panda‐Jonas (2020)
High Myopia and Glaucoma-Like Optic NeuropathyAsia-Pacific Journal of Ophthalmology (Philadelphia, Pa.), 9
R. Bourne, S. Flaxman, T. Braithwaite, M. Cicinelli, Aditi Das, J. Jonas, J. Keeffe, J. Kempen, J. Leasher, H. Limburg, K. Naidoo, K. Pesudovs, S. Resnikoff, Alex Silvester, Gretchen Stevens, N. Tahhan, T. Wong, H. Taylor (2017)
Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis.The Lancet. Global health, 5 9
Increasing evidence indicates that improving ocular blood flow (OBF) can be a therapeutic direction for glaucoma therapy. Tafluprost, a prostaglandin analogue which lowers the intraocular pressure (IOP), has been shown to improve OBF in animals and humans. Several animal experiments showed that topical tafluprost significantly increased optic nerve head and retinal blood flow. Clinical trials also showed a beneficial effect of tafluprost on optic nerve head and macula blood flow, and a good ocular pulse amplitude-lowering effect. But, there are still a few conflicting results. Overall, tafluprost seems to have a beneficial effect on OBF, and the positive effect is probably independent from its IOP-lowering effect, which also is expected to improve OBF. Moreover, reducing the intracellular free Ca2+ concentration may be a possible mechanism of tafluprost’s effect on OBF. More well-designed studies are required to reveal the truth.
Ophthalmology and Therapy – Springer Journals
Published: Dec 1, 2022
Keywords: Tafluprost; Prostaglandin analogues; Ocular blood flow; Microcirculation; Glaucoma
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