Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Randolph, K. Ginsburg, R. Leach, C. Blacker, K. Moghissi, M. Diamond, N. Reame (2003)
Elevated early follicular gonadotropin levels in women with unexplained infertility do not provide evidence for disordered gonadotropin-releasing hormone secretion as assessed by luteinizing hormone pulse characteristics.Fertility and sterility, 80 2
SL Choubisa (2015)
105India Fluoride, 48
J. Bódis, E. Sulyok, T. Kőszegi, K. Gödöny, V. Prémusz, Á. Várnagy (2018)
Serum and follicular fluid levels of sirtuin 1, sirtuin 6, and resveratrol in women undergoing in vitro fertilization: an observational, clinical studyThe Journal of International Medical Research, 47
Wenrong Li, Siyuan Dong, Qun Chen, Chen Chen, Zhaoheng Dong (2020)
Selenium may suppress peripheral blood mononuclear cell apoptosis by modulating HSP70 and regulate levels of SIRT1 through reproductive hormone secretion and oxidant stress in women suffering fluorosis.European journal of pharmacology
S. Choubisaa, Udaipur (2014)
INDUSTRIAL FLUOROSIS IN DOMESTIC GOATS ( CAPRA HIRCUS ) , RAJASTHAN , INDIA
S. D’Angelo, Elena Mele, Federico Filippo, A. Viggiano, R. Meccariello (2021)
Sirt1 Activity in the Brain: Simultaneous Effects on Energy Homeostasis and ReproductionInternational Journal of Environmental Research and Public Health, 18
M. Selvaggi, Claudia Carbonara, F. Ciotola, S. Albarella, G. Aiudi, V. Tufarelli, C. Dario (2019)
Determination of a possible relationship between a single nucleotide polymorphism (SNP) in the promoter region of the SIRT1 gene and production and reproduction traits in the Agerolese cattle breedArchives Animal Breeding, 62
Ami Shah, Isaac Nivar, D. Speelman (2018)
Elevated androstenedione in young adult but not early adolescent prenatally androgenized female ratsPLoS ONE, 13
G. Perera-Marín, C. Gutierrez, C. Murcia, H. León, E. González-Padilla (2008)
Progesterone and the distribution of pituitary gonadotropin isoforms in cattle.Animal reproduction science, 104 2-4
Irene Choi, Emily Rickert, M. Fernandez, N. Webster (2019)
SIRT1 in Astrocytes Regulates Glucose Metabolism and Reproductive Function.Endocrinology, 160 6
Anqi Wang, Qiang Ma, Biao Gong, Long Sun, Francis-Kojo Afrim, R. Sun, Tongkun He, Hui Huang, Jingyuan Zhu, Guoyu Zhou, Y. Ba (2021)
DNA methylation and fluoride exposure in school-age children: Epigenome-wide screening and population-based validation.Ecotoxicology and environmental safety, 223
M. Mascarenhas, S. Flaxman, T. Boerma, S. Vanderpoel, Gretchen Stevens (2012)
National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health SurveysPLoS Medicine, 9
Mingqiang Xu, Hao Jiang, Li-Qun Zhang, Xulei Sun, Dan Luo, Yao Fu, Yan Gao, Bao Yuan, Jiabao Zhang (2018)
MiR-29b affects the secretion of PROG and promotes the proliferation of bovine corpus luteum cellsPLoS ONE, 13
Xiaolong Gu, Dandan Han, Wei Chen, Limei Zhang, Qianyun Lin, Jian Gao, S. Fanning, B. Han (2016)
SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluorideOncotarget, 7
S. Meethal, Tianbing Liu, Hsien Chan, E. Ginsburg, Andrea Wilson, Danielle Gray, R. Bowen, B. Vonderhaar, C. Atwood (2009)
Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein‐dependent mechanism involving hypothalamic‐pituitary‐gonadal axis receptorsJournal of Neurochemistry, 110
Ullas Kolthur-Seetharam, K. Teerds, D. Rooij, O. Wendling, M. McBurney, P. Sassone-Corsi, I. Davidson (2009)
The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling1, 80
Qian Zhao, Z. Tian, Guoyu Zhou, Q. Niu, Jingwen Chen, Pei-Yuan Li, Lixin Dong, T. Xia, Shun Zhang, Ai-guo Wang (2020)
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluorideTheranostics, 10
J. Reimer, C. Schuster, Cameron Knight, D. Pang, D. Pang, Vivian Leung (2020)
Intraperitoneal injection of sodium pentobarbital has the potential to elicit pain in adult rats (Rattus norvegicus)PLoS ONE, 15
Yongjiang Zhou, Yiwen Qiu, Junlin He, Xuemei Chen, Yubin Ding, Yingxiong Wang, Xue-qing Liu (2013)
The toxicity mechanism of sodium fluoride on fertility in female rats.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 62
H. El-Sayyad, Mohamed Al-Haggar, Heba El-Ghawet, Iman Bakr (2014)
Effect of maternal diabetes and hypercholesterolemia on fetal liver of albino Wistar rats.Nutrition, 30 3
Debra Lynn, Gillian Brown (2009)
The Ontogeny of Exploratory Behavior in Male and Female Adolescent Rats (Rattus norvegicus)Developmental Psychobiology, 51
K. Smedlund, Jennifer Hill (2020)
The role of non-neuronal cells in hypogonadotropic hypogonadismMolecular and Cellular Endocrinology, 518
Qihao Weng, Fangyu Yi, Yingxiao Yu, Suyu Ge, Shangfeng Liu, Ying Zhang (2021)
Altered miRNA expression profiling in enamel organ of fluoride affected rat embryos.Ecotoxicology and environmental safety, 210
M. Hunter, R. Robinson, G. Mann, R. Webb (2004)
Endocrine and paracrine control of follicular development and ovulation rate in farm species.Animal reproduction science, 82-83
M. Haigis, D. Sinclair (2010)
Mammalian sirtuins: biological insights and disease relevance.Annual review of pathology, 5
E. Bosch, C. Alviggi, M. Lispi, A. Conforti, A. Hanyaloglu, D. Chuderland, M. Simoni, N. Raine-Fenning, P. Crépieux, S. Kol, V. Rochira, T. D'Hooghe, P. Humaidan (2021)
Reduced FSH and LH action: implications for medically assisted reproductionHuman Reproduction (Oxford, England), 36
A. Sen, Hanne Hoffmann (2019)
Role of core circadian clock genes in hormone release and target tissue sensitivity in the reproductive axisMolecular and Cellular Endocrinology, 501
C. Tatone, G. Emidio, Arcangelo Barbonetti, G. Carta, A. Luciano, S. Falone, F. Amicarelli (2018)
Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility.Human reproduction update, 24 3
Yongjiang Zhou, Hailing Zhang, Junlin He, Xuemei Chen, Yubin Ding, Yingxiong Wang, Xue-qing Liu (2013)
Effects of sodium fluoride on reproductive function in female rats.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 56
Tatiane Faria, Flávia Brasil, F. Sampaio, C. Ramos (2010)
Effects of maternal undernutrition during lactation on estrogen and androgen receptor expressions in rat ovary at puberty.Nutrition, 26 10
R. Gaspar, R. Benevides, J. Fontelles, C. Vale, L. França, P. Barros, A. Paes (2016)
Reproductive alterations in hyperinsulinemic but normoandrogenic MSG obese female rats.The Journal of endocrinology, 229 2
OA Oke (1999)
169Trop Vet, 17
Yi-Xun Liu, A. Hsueh (1986)
Synergism between granulosa and theca-interstitial cells in estrogen biosynthesis by gonadotropin-treated rat ovaries: studies on the two-cell, two-gonadotropin hypothesis using steroid antisera.Biology of reproduction, 35 1
(1999)
Vaginal cytological changes during the oestrous cycle of the adult female African giant rat (Cricetomys gambianus Waterhouse)
H. Kabir, A. Gupta, S. Tripathy (2020)
Fluoride and human health: Systematic appraisal of sources, exposures, metabolism, and toxicityCritical Reviews in Environmental Science and Technology, 50
M. Szczuko, Joanna Splinter, M. Zapałowska-Chwyć, Maciej Ziętek, D. Maciejewska (2019)
Fluorine may intensify the mechanisms of polycystic ovary syndrome (PCOS) development via increased insulin resistance and disturbed thyroid-stimulating hormone (TSH) synthesis even at reference levels.Medical hypotheses, 128
Guo-yan Liu, Weidong Zhang, P. Jiang, Xinhong Li, Chun-Yan Liu, Chun-yan Chai (2012)
Role of nitric oxide and vascular endothelial growth factor in fluoride-induced goitrogenesis in rats.Environmental toxicology and pharmacology, 34 2
M. Zhao, Guo-yu Zhou, Jingyuan Zhu, Biao Gong, Jia-xiang Hou, Tong Zhou, Lijv Duan, Zhong Ding, Liuxin Cui, Y. Ba (2015)
Fluoride Exposure, Follicle Stimulating Hormone Receptor Gene Polymorphism and Hypothalamus-pituitary-ovarian Axis Hormones in Chinese Women.Biomedical and environmental sciences : BES, 28 9
A. Ulloa-Aguirre, R. Espinoza, P. Damián-Matsumura, F. Larrea, A. Flores, L. Morales, R. Domínguez (1988)
Studies on the microheterogeneity of anterior pituitary follicle-stimulating hormone in the female rat. Isoelectric focusing pattern throughout the estrous cycle.Biology of reproduction, 38 1
Lin Yan, Xiao-long Bai, Z. Fang, L. Che, Shengyu Xu, De Wu (2013)
Effect of different dietary omega-3/omega-6 fatty acid ratios on reproduction in male ratsLipids in Health and Disease, 12
M. Khawar, Abdullah Sohail, Wei Li (2022)
SIRT1: A Key Player in Male ReproductionLife, 12
Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
Lipirani Jana, Pikash Maity, Hasina Perveen, Moumita Dash, S. Jana, Arindam Dey, S. De, S. Chattopadhyay (2018)
Attenuation of utero-toxicity, metabolic dysfunction and inflammation by soy protein concentrate in rats exposed to fluoridated water: consequence of hyperlipidemia in parallel with hypohomocysteinemiaEnvironmental Science and Pollution Research, 25
Fluorosis causes female reproductive dysfunction with reduced fertility without established pathogenesis. To clarify the mechanism, Sprague–Dawley female rats were selected with drinking water containing 0, 50 (low), 100 (moderate), and 150 mg/L (high) sodium fluoride (NaF) for a short (2 months), medium (4 months), and long term (6 months). The water consumption and body weight of female rats were recorded daily. The effect of NaF on the estrous cycle was examined by vaginal smears and recorded in different term treatments. Female and male rats were mated in a 2:1 ratio for 1 week at 2-, 4-, and 6-month treatment time for mating performance and fertility rate. Selected female rats were executed for tissue and blood collection at different treatment terms. Twenty-four-hour urine sample from each female rat was collected using the metabolic cage. The levels of steroid hormones and silent information regulator 2 homolog 1 (SIRT1) in serum were measured by appropriate ELISA kits. Body weight of the high NaF group was significantly less during short-term treatment than that of other treatment groups or control group. Urinary fluoride concentration was increased linearly with treatment time. Treatment of NaF significantly decreased steroid hormone level while increased SIRT1 level in the serum. In addition, NaF treatment significantly decreased pregnancy rate. It is concluded that NaF inhibits the secretion of hormone and estradiol (E2) release from the ovary, thereby reducing the rate of pregnant. SIRT1 may be involved in this NaF-induced reproductive dysfunction in female rats through regulating reproductive hormone, FSH, and LH secretion.
Biological Trace Element Research – Springer Journals
Published: Apr 1, 2023
Keywords: NaF; Reproductive function; Fluorosis; SIRT1; Steroid hormone
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.