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Effect of mutation on synthesis of alkaloid byPenicillium roquefortii VKM F-141 andP. fellutanum VKM F-1073

Effect of mutation on synthesis of alkaloid byPenicillium roquefortii VKM F-141 andP. fellutanum... Mutant strains ofPenicillium roquefortii VKM F-141 andP. fellutanum VKM F-1073 were obtained by mutagenesis induced by ultraviolet irradiation,N-methyl-N-nitronitrosoguanidine, and bromouracil. By the rates of alkaloid production, the mutant strains can be divided into three groups: (1) unable to synthesize alkaloids; (2) with a high rate of biosynthesis; (3) with changed alkaloid composition. Compounds not characteristic of wild-type cultures were found in alkaloid fractions of some mutant strains. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Biochemistry and Microbiology Springer Journals

Effect of mutation on synthesis of alkaloid byPenicillium roquefortii VKM F-141 andP. fellutanum VKM F-1073

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References (4)

Publisher
Springer Journals
Copyright
Copyright © 2000 by MAIK “Nauka/Interperiodica”
Subject
Life Sciences; Biochemistry, general; Microbiology; Medical Microbiology
ISSN
0003-6838
eISSN
1608-3024
DOI
10.1007/BF02742580
Publisher site
See Article on Publisher Site

Abstract

Mutant strains ofPenicillium roquefortii VKM F-141 andP. fellutanum VKM F-1073 were obtained by mutagenesis induced by ultraviolet irradiation,N-methyl-N-nitronitrosoguanidine, and bromouracil. By the rates of alkaloid production, the mutant strains can be divided into three groups: (1) unable to synthesize alkaloids; (2) with a high rate of biosynthesis; (3) with changed alkaloid composition. Compounds not characteristic of wild-type cultures were found in alkaloid fractions of some mutant strains.

Journal

Applied Biochemistry and MicrobiologySpringer Journals

Published: Nov 6, 2007

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