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Effect of iohexol on tear production and the fluctuations of Schirmer tear test values in clinically normal donkeys

Effect of iohexol on tear production and the fluctuations of Schirmer tear test values in... Dacryocystography has been widely used in the assessment of the nasolacrimal duct system, particularly in patients with epiphora. The site of obstruction and presence of fistulas, tumor, diverticula, or calculi can be delineated so that therapy can be accurately planned. The water-soluble agent iohexol is currently widely used in nervous and vascular lesions in diagnostic radiology and also employed in dacryocystography. The aim of this study was to investigate the effects of iohexol on tear production and normal fluctuations of Schirmer tear test (STT) values in donkeys. The STT of ten normal donkeys were determined, which were done pre- and post-treatment of iohexol during dacryocystography. Schirmer tear test was performed at 0 h, 2 h, and 2 weeks pre- and post-dacryocystography with iohexol. All donkeys were housed outdoors throughout the study. There were no significant differences in tear production before and after administration of iohexol. The slight fluctuations in STT may be as a result of individual and/or environmental changes. Iohexol did not change STT values of the donkeys in this study. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

Effect of iohexol on tear production and the fluctuations of Schirmer tear test values in clinically normal donkeys

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References (25)

Publisher
Springer Journals
Copyright
Copyright © 2008 by Springer-Verlag London Limited
Subject
Medicine & Public Health; Oncology ; Hematology; Pathology
eISSN
1618-565X
DOI
10.1007/s00580-008-0746-y
Publisher site
See Article on Publisher Site

Abstract

Dacryocystography has been widely used in the assessment of the nasolacrimal duct system, particularly in patients with epiphora. The site of obstruction and presence of fistulas, tumor, diverticula, or calculi can be delineated so that therapy can be accurately planned. The water-soluble agent iohexol is currently widely used in nervous and vascular lesions in diagnostic radiology and also employed in dacryocystography. The aim of this study was to investigate the effects of iohexol on tear production and normal fluctuations of Schirmer tear test (STT) values in donkeys. The STT of ten normal donkeys were determined, which were done pre- and post-treatment of iohexol during dacryocystography. Schirmer tear test was performed at 0 h, 2 h, and 2 weeks pre- and post-dacryocystography with iohexol. All donkeys were housed outdoors throughout the study. There were no significant differences in tear production before and after administration of iohexol. The slight fluctuations in STT may be as a result of individual and/or environmental changes. Iohexol did not change STT values of the donkeys in this study.

Journal

Comparative Clinical Pathology – Springer Journals

Published: Jun 14, 2008

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