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ISSN 0012-5008, Doklady Chemistry, 2007, Vol. 416, Part 1, pp. 205–206. © Pleiades Publishing, Ltd., 2007. Original Russian Text © N.N. Glagolev, N.A. Aksenova, S.Z. Rogovina, A.B. Solov’eva, 2007, published in Doklady Akademii Nauk, 2007, Vol. 416, No. 1, pp. 57–59. CHEMISTRY Effect of Amino-Containing Polymers on the Photocatalytic Activity of Water-Soluble Porphyrin Sensitizers N. N. Glagolev, N. A. Aksenova, S. Z. Rogovina, and A. B. Solov’eva Presented by Academician Al.Al. Berlin April 9, 2007 Received April 13, 2007 DOI: 10.1134/S0012500807090017 Porphyrin photosensitizers (PPSs) immobilized on tration upon photooxidation over time ∆ t. The error of polymer carriers are used in both catalytic processes determination of k was 10%. eff involving singlet oxygen ( é ) and photodynamic ther- Figure 1 shows the plots of k of the photooxidation eff apy (PDT) of tumors. The latter is due to their tumoro- of tryptophan catalyzed by dimegin (curves 1–3) and tropism and biocompatibility. When used in PDT, é TSMPP (curves 4, 5) versus the concentration of CTS oxidizes cell components and initiates a cascade of pro- (curves 2, 5), PAA (curve 3), and CMC (curves 1, 4) in cesses leading to the death of tumor cells. The possibil- the system.
Doklady Chemistry – Springer Journals
Published: Sep 26, 2007
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