Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Diffuse type testicular seminoma in a stallion

Diffuse type testicular seminoma in a stallion A 7-year-old stallion with progressive left testicular enlargement was presented. Grossly, the excised testicle measured 25 × 15 × 12 cm and weighed 3.7 kg. It was multinodular with a gray-white surface; however, the right testis was normal. Histologically, the neoplastic cells were disseminated diffusely in the tumoral stroma with a minimal fibrovascular stroma. Neoplastic cells were round to polygonal with abundant eosinophilic cytoplasm and large round to oval vesicular or hyperchromatic nucleous with a single prominent nucleolus. Immunohistochemically, the neoplastic cells were positive nuclear immunostaining for C-KIT and negative for OCT3/4. According to gross, histopathological, and immunohistochemical characteristics, the diffuse type of seminoma was diagnosed. Nine months later, the follow-up observation of the case showed that the tumor had no recurrence and metastasis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

Diffuse type testicular seminoma in a stallion

Download PDF
4 pages

Loading next page...
 
/lp/springer-journals/diffuse-type-testicular-seminoma-in-a-stallion-ltrbpt0L9T
Publisher
Springer Journals
Copyright
Copyright © 2016 by The Author(s)
Subject
Medicine & Public Health; Pathology; Hematology; Oncology
eISSN
1618-565X
DOI
10.1007/s00580-016-2316-z
Publisher site
See Article on Publisher Site

Abstract

A 7-year-old stallion with progressive left testicular enlargement was presented. Grossly, the excised testicle measured 25 × 15 × 12 cm and weighed 3.7 kg. It was multinodular with a gray-white surface; however, the right testis was normal. Histologically, the neoplastic cells were disseminated diffusely in the tumoral stroma with a minimal fibrovascular stroma. Neoplastic cells were round to polygonal with abundant eosinophilic cytoplasm and large round to oval vesicular or hyperchromatic nucleous with a single prominent nucleolus. Immunohistochemically, the neoplastic cells were positive nuclear immunostaining for C-KIT and negative for OCT3/4. According to gross, histopathological, and immunohistochemical characteristics, the diffuse type of seminoma was diagnosed. Nine months later, the follow-up observation of the case showed that the tumor had no recurrence and metastasis.

Journal

Comparative Clinical Pathology – Springer Journals

Published: Aug 9, 2016

References

  • Bilateral testicular seminoma in a New Zealand white rabbit
    Anderson, WI; Car, BD; Kenny, K; Schlafer, DH
  • Ultrasound appearance of an equine testicular seminoma
    Beck, C; Charles, JA; Maclean, AA
  • Establishing a germ cell origin for metastatic tumors using OCT4 immunohistochemistry
    Cheng, L
  • The use of immunohistochemistry in the differential diagnosis of tumors of the testis and paratestis
    Emerson, RE; Ulbright, TM
  • Kangal irki bir kopekte sertoli hucreli tumor ve seminoma
    Erer, H; Kiran, MM; Yavru, N
  • Classical and spermatocytic seminoma in the dog: histochemical and immunohistochemical findings
    Grieco, EV; Riccardi, M; Rondena, V; Ciampi Finazzi, M
  • Canine Brusellosis: outbreaks and compliance
    Hollet, RB
  • Canine testicular tumors: two types of seminomas can be differentiated by immunohistochemistry
    Hohsteter, M; Artukovic, M; Severin, K; Kurilj, AG; Beck, A; Sostaric-Zuckermann, IC; Grabarevic, Z
  • Canine and feline theriogenology
    Johnston, SD; Kustritz, MR; Onson, PS
  • D2-40 immunohistochemistry in the differential diagnosis of seminoma and embryonal carcinoma: a comparative immunohistochemical study with KIT (CD117) and CD30
    Lau, SK; Weiss, LM; Chu, PG
  • Fundamentos de terapia intensiva veterinária em pequenos animais condutas no paciente crítico
    Macintire, DK; Ferreira, LF; Vianna, RA
  • Tumors in domestic animals
    MacLachlan, NJ; Kennedy, PC
  • Correlation of nuclear morphometric features with animal and human world health organization international histological classifications of canine spontaneous seminomas
    Maiolino, P; Restucci, B; Papparella, S; Paciello, O; Vico, GD
  • Interstitial cell tumor and sertoli cell tumor in the testis of a cat
    Miller, MA; Hartnett, SE; Ramos-Vara, JA
  • Cancer in dog and cats: medical and surgical management
    Morrison, WB
  • KIT (c-KIT oncogene product) pathway is constitutively activated in human testicular germ cell tumors
    Nakai, Y; Nonomura, N; Oka, D; Shiba, M; Arai, Y; Nakayama, M; Inoue, H; Nishimura, K; Aozasa, K; Mizutani, Y; Miki, T; Okuyama, A
  • Medicina Interna de Pequenos Animais
    Nelson, RW; Couto, CG
  • Use of antibodies against LH receptor, 3beta-h droxysteroid dehydrogenase and vimentin to characterize different types of testicular tumour in dogs
    Peters, MA; Teerds, KJ; Gaag, I; Rooij, DG; Van Sluijs, FJ
  • Rosai and Ackerman’s surgical pathology
    Rosai, J
  • OCT4 is superior to CD30 in the diagnosis of metastatic embryonal carcinomas after chemotherapy
    Sung, MT; Jones, TD; Beck, SD; Foster, RS; Cheng, L
  • Morphological and immunohistochemical characterisation of seminomas in Norwegian dogs
    Thorvaldsen, TE; Nodtvedt, A; Grotmol, T; Gunnes, G
  • World Health Organization classiffication of tumors. Pathology & Genetics. Tumors of the urinary system and male genital organs
    Woodward, PJ; Heindereich, A; Looijenga, LHJ; Osterhuis, JW; McLeod, DG; Moller, H; Manivel, JC; Mostofi, FK; Hailemariam, S; Parkinson, MC; Grigor, K; True, L; Jacobsen, GK; Oliver, TD; Talerman, A; Kaplan, GW; Ulbright, TH; Sesterhenn, IA; Rushton, HG; Michael, H; Reuter, VE