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Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases

Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome... Oncol Ther (2016) 4:199–210 DOI 10.1007/s40487-016-0026-y ORIGINAL RESEARCH Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases . . . . Marion Wobser Theresa Reinartz Sabine Roth Matthias Goebeler Andreas Rosenwald Eva Geissinger Received: May 9, 2016 / Published online: August 18, 2016 The Author(s) 2016. This article is published with open access at Springerlink.com until 2015. Cytological, histological, ABSTRACT immunohistochemical and molecular genetic Introduction: Cytotoxic CD8? T-cell features were assessed and correlated with lymphomas are only rarely encountered and respective clinical data. thus remain only poorly characterized. Our aim Results: The identified cases of CD8? cytotoxic was to collect and correlate clinical and atypical lymphoproliferative infiltrates of the histological data of CD8? skin lymphoma skin (n = 35) comprised 13 cases of mycosis infiltrates to obtain a proper subtype fungoides (MF)/Se´zary syndrome (SS), 4 cases of assignment of CD8? skin lymphoma subcutaneous panniculitis-like T-cell infiltrates and to derive putative prognostic lymphoma (SPTCL), 5 cases of primary markers thereof. cutaneous acral CD8? lymphoma [formerly Methods: Formalin-fixed and indolent CD8? lymphoid proliferation (ILP)] paraffin-embedded (FFPE) tissue of 35 patients and 1 case of aggressive epidermotropic primary with CD8? cytotoxic cutaneous T-cell cutaneous T-cell lymphoma (AECTCL). lymphoma http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Oncology and Therapy Springer Journals

Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases

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Publisher
Springer Journals
Copyright
Copyright © 2016 by The Author(s)
Subject
Medicine & Public Health; Internal Medicine
ISSN
2366-1070
eISSN
2366-1089
DOI
10.1007/s40487-016-0026-y
Publisher site
See Article on Publisher Site

Abstract

Oncol Ther (2016) 4:199–210 DOI 10.1007/s40487-016-0026-y ORIGINAL RESEARCH Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases . . . . Marion Wobser Theresa Reinartz Sabine Roth Matthias Goebeler Andreas Rosenwald Eva Geissinger Received: May 9, 2016 / Published online: August 18, 2016 The Author(s) 2016. This article is published with open access at Springerlink.com until 2015. Cytological, histological, ABSTRACT immunohistochemical and molecular genetic Introduction: Cytotoxic CD8? T-cell features were assessed and correlated with lymphomas are only rarely encountered and respective clinical data. thus remain only poorly characterized. Our aim Results: The identified cases of CD8? cytotoxic was to collect and correlate clinical and atypical lymphoproliferative infiltrates of the histological data of CD8? skin lymphoma skin (n = 35) comprised 13 cases of mycosis infiltrates to obtain a proper subtype fungoides (MF)/Se´zary syndrome (SS), 4 cases of assignment of CD8? skin lymphoma subcutaneous panniculitis-like T-cell infiltrates and to derive putative prognostic lymphoma (SPTCL), 5 cases of primary markers thereof. cutaneous acral CD8? lymphoma [formerly Methods: Formalin-fixed and indolent CD8? lymphoid proliferation (ILP)] paraffin-embedded (FFPE) tissue of 35 patients and 1 case of aggressive epidermotropic primary with CD8? cytotoxic cutaneous T-cell cutaneous T-cell lymphoma (AECTCL). lymphoma

Journal

Oncology and Therapy – Springer Journals

Published: Aug 18, 2016

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