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Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F-18 FDG Administration as Effective Alternatives to Intravenous Administration in Mouse Tumor Models Using Small Animal PET/CT Studies

Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F-18 FDG Administration... Nucl Med Mol Imaging (2011) 45:169–176 DOI 10.1007/s13139-011-0087-7 ORIGINAL ARTICLE Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F-18 FDG Administration as Effective Alternatives to Intravenous Administration in Mouse Tumor Models Using Small Animal PET/CT Studies Chulhan Kim & In Hye Kim & Seo-il Kim & Young Sang Kim & Se Hun Kang & Seung Hwan Moon & Tae-Sung Kim & Seok-ki Kim Received: 30 December 2010 /Accepted: 1 May 2011 /Published online: 27 May 2011 Korean Society of Nuclear Medicine 2011 Abstract PO administration group, tumoral uptake was delayed and Purpose We compared alternative routes for F-fluorodeox- reduced. There was no statistical difference among the RO, IP yglucose (FDG) administration, such as the retroorbital and IV administration groups for additional serial PET scans. (RO), intraperitoneal (IP) and per oral (PO) routes, with the Conclusion RO administration is an effective alternative intravenous (IV) route in normal tissues and tumors of mice. route to IV administration for mouse FDG PET scans using Materials and Methods CRL-1642 (ATCC, Lewis lung normal mice and tumor models. In addition, IP administration carcinoma) cells were inoculated in female BALB/c-nu/nu can be a practical alternative in the late phase, although the mice 6 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nuclear Medicine and Molecular Imaging Springer Journals

Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F-18 FDG Administration as Effective Alternatives to Intravenous Administration in Mouse Tumor Models Using Small Animal PET/CT Studies

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References (13)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Korean Society of Nuclear Medicine
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Cardiology; Orthopedics; Oncology
ISSN
1869-3474
eISSN
1869-3482
DOI
10.1007/s13139-011-0087-7
pmid
24900000
Publisher site
See Article on Publisher Site

Abstract

Nucl Med Mol Imaging (2011) 45:169–176 DOI 10.1007/s13139-011-0087-7 ORIGINAL ARTICLE Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F-18 FDG Administration as Effective Alternatives to Intravenous Administration in Mouse Tumor Models Using Small Animal PET/CT Studies Chulhan Kim & In Hye Kim & Seo-il Kim & Young Sang Kim & Se Hun Kang & Seung Hwan Moon & Tae-Sung Kim & Seok-ki Kim Received: 30 December 2010 /Accepted: 1 May 2011 /Published online: 27 May 2011 Korean Society of Nuclear Medicine 2011 Abstract PO administration group, tumoral uptake was delayed and Purpose We compared alternative routes for F-fluorodeox- reduced. There was no statistical difference among the RO, IP yglucose (FDG) administration, such as the retroorbital and IV administration groups for additional serial PET scans. (RO), intraperitoneal (IP) and per oral (PO) routes, with the Conclusion RO administration is an effective alternative intravenous (IV) route in normal tissues and tumors of mice. route to IV administration for mouse FDG PET scans using Materials and Methods CRL-1642 (ATCC, Lewis lung normal mice and tumor models. In addition, IP administration carcinoma) cells were inoculated in female BALB/c-nu/nu can be a practical alternative in the late phase, although the mice 6

Journal

Nuclear Medicine and Molecular Imaging – Springer Journals

Published: May 27, 2011

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