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- Publisher
- Springer Journals
- Copyright
- Copyright © 2013 by Springer International Publishing Switzerland
- Subject
- Medicine & Public Health; Cardiology; Pharmacotherapy; Pharmacology/Toxicology
- ISSN
- 1175-3277
- eISSN
- 1179-187X
- DOI
- 10.1007/s40256-013-0039-y
- pmid
- 23913405
- Publisher site
- See Article on Publisher Site
Abstract
Am J Cardiovasc Drugs (2013) 13:413–424 DOI 10.1007/s40256-013-0039-y OR IGINAL RESEARCH ARTIC L E Comparison of Antiplatelet Effect and Safety of Clopidogrel Napadisilate with Clopidogrel Bisulfate in Coronary Artery Disease Patients: Multi-center, Randomized, Double-blind, Phase IV, Non-inferiority Clinical Trial • • • Sahmin Lee Hae-Young Lee Kyung-Woo Park • • • Hyun-Jae Kang Bon-Kwon Koo Hyo-Soo Kim • • Dong-Ju Choi Myung-A Kim Byung-Hee Oh Published online: 3 August 2013 Springer International Publishing Switzerland 2013 Abstract months prior and had remained in a stable condition with a Background Clopidogrel napadisilate has better clopido- single antiplatelet agent, aspirin. grel stability than clopidogrel bisulfate. There are no data, Methods This study was a prospective, randomized, however, on the antiplatelet efficacy and tolerability of double-blind, double-dummy, parallel-group, phase IV clopidogrel napadisilate in coronary artery disease (CAD) clinical trial. A total of 162 patients were prospectively patients. recruited from three centers. The subjects were randomized Objective The aim of this study is to demonstrate that the to either the test group that was treated with 75 mg of combination therapy of aspirin and clopidogrel napadisilate clopidogrel napadisilate once daily or to the control group is not inferior to that of aspirin and clopidogrel
Journal
American Journal of Cardiovascular Drugs – Springer Journals
Published: Aug 3, 2013