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Purpose The aim of this study was to evaluate the clinical astatic lung nodules, 66 nodules were diagnosed as meta- usefulness of additional low-dose high-resolution lung com- static. Eleven of the 66 nodules were confirmed histopath- puted tomography (LD-HRCT) combined with F-fluoro-2- ologically and the others were diagnosed by clinical fol- 18 18 deoxyglucose positron emission tomography with CT ( F- low-up. Conventional lung setting image of F-FDG PET/ FDG PET/CT) compared with conventional lung setting im- CT detected 40 of the 66 nodules and additional LD-HRCT age of F-FDG PET/CT for the detection of metastatic lung detected 55 nodules. All 15 nodules missed by convention- nodules from colorectal cancer. al lung setting imaging but detected by additional LD- Methods From January 2011 to September 2011, 649 patients HRCT were<1 cm in size. The sensitivity, specificity, and with colorectal cancer underwent additional LD-HRCT at diagnostic accuracy of the modalities were 60.6 %, 85.2 %, maximum inspiration combined with F-FDG PET/CT. and 71.1 % for conventional lung setting image and Forty-five patients were finally diagnosed to have lung metas- 83.3 %, 88.9 %, and 85.8 % for additional LD-HRCT. By tasis based on histopathologic study or clinical follow-up. ROCanalysis, theareaunder
Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Dec 17, 2015
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