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Clinical Value of a One-Stop-Shop Low-Dose Lung Screening Combined with 18F-FDG PET/CT for the Detection of Metastatic Lung Nodules from Colorectal Cancer

Clinical Value of a One-Stop-Shop Low-Dose Lung Screening Combined with 18F-FDG PET/CT for the... Purpose The aim of this study was to evaluate the clinical astatic lung nodules, 66 nodules were diagnosed as meta- usefulness of additional low-dose high-resolution lung com- static. Eleven of the 66 nodules were confirmed histopath- puted tomography (LD-HRCT) combined with F-fluoro-2- ologically and the others were diagnosed by clinical fol- 18 18 deoxyglucose positron emission tomography with CT ( F- low-up. Conventional lung setting image of F-FDG PET/ FDG PET/CT) compared with conventional lung setting im- CT detected 40 of the 66 nodules and additional LD-HRCT age of F-FDG PET/CT for the detection of metastatic lung detected 55 nodules. All 15 nodules missed by convention- nodules from colorectal cancer. al lung setting imaging but detected by additional LD- Methods From January 2011 to September 2011, 649 patients HRCT were<1 cm in size. The sensitivity, specificity, and with colorectal cancer underwent additional LD-HRCT at diagnostic accuracy of the modalities were 60.6 %, 85.2 %, maximum inspiration combined with F-FDG PET/CT. and 71.1 % for conventional lung setting image and Forty-five patients were finally diagnosed to have lung metas- 83.3 %, 88.9 %, and 85.8 % for additional LD-HRCT. By tasis based on histopathologic study or clinical follow-up. ROCanalysis, theareaunder http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nuclear Medicine and Molecular Imaging Springer Journals

Clinical Value of a One-Stop-Shop Low-Dose Lung Screening Combined with 18F-FDG PET/CT for the Detection of Metastatic Lung Nodules from Colorectal Cancer

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References (24)

Publisher
Springer Journals
Copyright
Copyright © 2015 by Korean Society of Nuclear Medicine
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology
ISSN
1869-3474
eISSN
1869-3482
DOI
10.1007/s13139-015-0387-4
pmid
27275363
Publisher site
See Article on Publisher Site

Abstract

Purpose The aim of this study was to evaluate the clinical astatic lung nodules, 66 nodules were diagnosed as meta- usefulness of additional low-dose high-resolution lung com- static. Eleven of the 66 nodules were confirmed histopath- puted tomography (LD-HRCT) combined with F-fluoro-2- ologically and the others were diagnosed by clinical fol- 18 18 deoxyglucose positron emission tomography with CT ( F- low-up. Conventional lung setting image of F-FDG PET/ FDG PET/CT) compared with conventional lung setting im- CT detected 40 of the 66 nodules and additional LD-HRCT age of F-FDG PET/CT for the detection of metastatic lung detected 55 nodules. All 15 nodules missed by convention- nodules from colorectal cancer. al lung setting imaging but detected by additional LD- Methods From January 2011 to September 2011, 649 patients HRCT were<1 cm in size. The sensitivity, specificity, and with colorectal cancer underwent additional LD-HRCT at diagnostic accuracy of the modalities were 60.6 %, 85.2 %, maximum inspiration combined with F-FDG PET/CT. and 71.1 % for conventional lung setting image and Forty-five patients were finally diagnosed to have lung metas- 83.3 %, 88.9 %, and 85.8 % for additional LD-HRCT. By tasis based on histopathologic study or clinical follow-up. ROCanalysis, theareaunder

Journal

Nuclear Medicine and Molecular ImagingSpringer Journals

Published: Dec 17, 2015

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