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S. Brietzke, Jennifer Shin, Sukgi Choi, Jivianne Lee, S. Parikh, M. Peña, J. Prager, H. Ramadan, Maria Veling, Maureen Corrigan, R. Rosenfeld (2014)
Clinical Consensus StatementOtolaryngology–Head and Neck Surgery, 151
D. Badr, J. Gaffin, W. Phipatanakul (2016)
Pediatric RhinosinusitisCurrent Treatment Options in Allergy, 3
Katherine Tuttle, T. Schneider, S. Henrickson, David Morris, J. Abonia, J. Spergel, T. Laidlaw (2016)
Aspirin-exacerbated respiratory disease: not always "adult-onset".The journal of allergy and clinical immunology. In practice, 4 4
M. Yung, J. Gould, G. Upton (2002)
Nasal Polyposis in Children with Cystic Fibrosis: A Long-Term Follow-up StudyAnnals of Otology, Rhinology & Laryngology, 111
Nick Jones, A. Strobl, I. Holland (1997)
A study of the CT findings in 100 patients with rhinosinusitis and 100 controls.Clinical otolaryngology and allied sciences, 22 1
G. DeMuri, E. Wald (2013)
Acute bacterial sinusitis in children.Pediatrics in review, 34 10
Sapideh Gilani, Jennifer Shin (2017)
The Burden and Visit Prevalence of Pediatric Chronic RhinosinusitisOtolaryngology–Head and Neck Surgery, 157
J. Kennedy, L. Borish (2013)
Chronic sinusitis pathophysiology: The role of allergy, 27
A. Talaat, Y. Bahgat, E. El-Ghazzawy, Samy Elwany (1989)
Nasopharyngeal bacterial flora before and after adenoidectomyThe Journal of Laryngology & Otology, 103
A. Fretzayas, M. Moustaki (2016)
Clinical spectrum of primary ciliary dyskinesia in childhood.World journal of clinical pediatrics, 5 1
M. Coren, M. Meeks, I. Morrison, R. Buchdahl, A. Bush (2002)
Primary ciliary dyskinesia: age at diagnosis and symptom historyActa Pædiatrica, 91
M. Berges-Gimeno, R. Simon, D. Stevenson (2002)
The natural history and clinical characteristics of aspirin-exacerbated respiratory disease.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 89 5
Patrick Hosie, D. Fitzgerald, A. Jaffe, C. Birman, J. Rutland, L. Morgan (2015)
Presentation of primary ciliary dyskinesia in children: 30 years' experienceJournal of Paediatrics and Child Health, 51
J. Levy, L. Rudmik, Anju Peters, S. Wise, B. Rotenberg, Timothy Smith (2016)
Contemporary management of chronic rhinosinusitis with nasal polyposis in aspirin‐exacerbated respiratory disease: an evidence‐based review with recommendationsInternational Forum of Allergy & Rhinology, 6
P. Gevaert, N. Bruaene, T. Cattaert, K. Steen, T. Zele, F. Acke, N. Ruyck, Katrien Blomme, A. Sousa, R. Marshall, C. Bachert (2011)
Rhinitis , sinusitis , and upper airway disease Mepolizumab , a humanized anti – IL-5 mAb , as a treatment option for severe nasal polyposis
R. Younis, Vinod Anand, B. Davidson (2002)
The Role of Computed Tomography and Magnetic Resonance Imaging in Patients With Sinusitis With ComplicationsThe Laryngoscope, 112
A. Magit (2014)
Pediatric rhinosinusitis.Otolaryngologic clinics of North America, 47 5
A. Foreman, S. Boase, A. Psaltis, P. Wormald (2012)
Role of Bacterial and Fungal Biofilms in Chronic RhinosinusitisCurrent Allergy and Asthma Reports, 12
H. Ramadan (2009)
Revision endoscopic sinus surgery in childrenThe Laryngoscope, 119
G. Nishioka, P. Cook, W. Davis, Joel Mckinsey (1994)
Immunotherapy in Patients Undergoing Functional Endoscopic Sinus SurgeryOtolaryngology–Head and Neck Surgery, 110
D. Beswick, H. Ramadan, F. Baroody, P. Hwang (2016)
Practice Patterns in Pediatric Chronic Rhinosinusitis: A Survey of the American Rhinologic SocietyAmerican Journal of Rhinology & Allergy, 30
Kenny Chan, M. Abzug, L. Coffinet, E. Simões, C. Cool, A. Liu (2004)
Chronic rhinosinusitis in young children differs from adults: a histopathology study.The Journal of pediatrics, 144 2
Joshua Jervis‐Bardy, S. Boase, A. Psaltis, A. Foreman, P. Wormald (2012)
A randomized trial of mupirocin sinonasal rinses versus saline in surgically recalcitrant staphylococcal chronic rhinosinusitisThe Laryngoscope, 122
J. Coticchia, G. Zuliani, C. Coleman, M. Carron, José Gurrola, M. Haupert, R. Berk (2007)
Biofilm surface area in the pediatric nasopharynx: Chronic rhinosinusitis vs obstructive sleep apnea.Archives of otolaryngology--head & neck surgery, 133 2
Dharam Paul (1981)
Sinus infection and adenotonsillitis in pediatric patients.The Laryngoscope, 91
J. Steinke, D. Bradley, Pablo Arango, Charles Crouse, H. Frierson, S. Kountakis, M. Kraft, L. Borish (2003)
Cysteinyl leukotriene expression in chronic hyperplastic sinusitis-nasal polyposis: importance to eosinophilia and asthma.The Journal of allergy and clinical immunology, 111 2
J. Steinke, S. Payne, Philip Chen, J. Negri, E. Stelow, L. Borish (2012)
Etiology of Nasal Polyps in Cystic Fibrosis: Not a Unimodal DiseaseAnnals of Otology, Rhinology & Laryngology, 121
S. Brietzke, M. Brigger (2008)
Adenoidectomy outcomes in pediatric rhinosinusitis: a meta-analysis.International journal of pediatric otorhinolaryngology, 72 10
Dennis Lee, R. Rosenfeld (1997)
Adenoid Bacteriology and Sinonasal Symptoms in ChildrenOtolaryngology- Head and Neck Surgery, 116
I. Brook (2013)
Acute sinusitis in children.Pediatric clinics of North America, 60 2
K. Asakura, T. Kojima, H. Shirasaki, A. Kataura (1990)
Evaluation of the effects of antigen specific immunotherapy on chronic sinusitis in children with allergy.Auris, nasus, larynx, 17 1
N Kabaalioglu (2003)
39Kulak Burun Bogaz Ihtis Derg, 11
DC Lanza (1997)
S1Otolaryngol Head Neck Surg., 117
D Lee (1997)
301Otolaryngol Head Neck Surg, 116
I. Melén, A. Ivarsson, C. Schrewelius (1992)
Ostial function in allergic rhinitis.Acta oto-laryngologica. Supplementum, 492
J. McClay, B. Marple, L. Kapadia, M. Biavati, B. Nussenbaum, M. Newcomer, S. Manning, T. Booth, N. Schwade (2002)
Clinical Presentation of Allergic Fungal Sinusitis in ChildrenThe Laryngoscope, 112
Richard Rosenfeld (1995)
Pilot study of outcomes in pediatric rhinosinusitis.Archives of otolaryngology--head & neck surgery, 121 7
D. Lanza, D. Kennedy (1997)
Adult Rhinosinusitis DefinedOtolaryngology- Head and Neck Surgery, 117
J. Campbell, M. Graham, H. Gray, C. Bower, M. Blaiss, S. Jones (2006)
Allergic fungal sinusitis in children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 96 2
Nilgün Kabaalioğlu, K. Uygur, H. Yasan, A. Kabaalioğlu, H. Doğru (2003)
[The correlation between computed tomography findings of the paranasal sinuses and the symptoms of acute sinusitis].Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 11 2
J. Hagan, T. Laidlaw, R. Divekar, Erin O'Brien, H. Kita, G. Volcheck, Christina Hagan, D. Lal, H. Teaford, P. Erwin, Nan Zhang, M. Rank (2017)
Urinary Leukotriene E4 to Determine Aspirin Intolerance in Asthma: A Systematic Review and Meta-Analysis.The journal of allergy and clinical immunology. In practice, 5 4
C. Bachert, C. Bachert, L. Mannent, R. Naclerio, J. Mullol, B. Ferguson, P. Gevaert, P. Hellings, L. Jiao, Ling Wang, R. Evans, G. Pirozzi, N. Graham, B. Swanson, J. Hamilton, A. Radin, N. Gandhi, N. Stahl, G. Yancopoulos, E. Sutherland (2016)
Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial.JAMA, 315 5
M. Boita, M. Garzaro, L. Raimondo, G. Riva, J. Mazibrada, B. Vizio, G. Bellone, G. Pecorari, C. Bucca, G. Rolla, C. Giordano (2011)
The Expression of TSLP Receptor in Chronic Rhinosinusitis with and without Nasal PolypsInternational Journal of Immunopathology and Pharmacology, 24
T. Jartti, Maria Paul-Anttila, P. Lehtinen, V. Parikka, T. Vuorinen, O. Simell, O. Ruuskanen (2009)
Systemic T-helper and T-regulatory cell type cytokine responses in rhinovirus vs. respiratory syncytial virus induced early wheezing: an observational studyRespiratory Research, 10
Leigh Schwietz, D. Gourley (1992)
Allergic fungal sinusitis.Allergy proceedings : the official journal of regional and state allergy societies, 13 1
J. Steinke, S. Payne, L. Borish (2016)
Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease.Immunology and allergy clinics of North America, 36 4
D. Stevenson (2003)
Aspirin desensitization in patients with AERDClinical Reviews in Allergy & Immunology, 24
G. Leo, F. Triulzi, C. Incorvaia (2012)
Sinus Imaging for Diagnosis of Chronic Rhinosinusitis in ChildrenCurrent Allergy and Asthma Reports, 12
F. Ozturk, A. Bakirtas, F. Ileri, I. Turktas (2011)
Efficacy and tolerability of systemic methylprednisolone in children and adolescents with chronic rhinosinusitis: a double-blind, placebo-controlled randomized trial.The Journal of allergy and clinical immunology, 128 2
G. Zuliani, M. Carron, José Gurrola, C. Coleman, M. Haupert, R. Berk, J. Coticchia (2006)
Identification of adenoid biofilms in chronic rhinosinusitis.International journal of pediatric otorhinolaryngology, 70 9
J. Steinke, S. Payne, M. Tessier, L. Borish, Joseph Han, L. Borish (2009)
Pilot study of budesonide inhalant suspension irrigations for chronic eosinophilic sinusitis.The Journal of allergy and clinical immunology, 124 6
B. Liao, P. Cao, M. Zeng, Zhen Zhen, Zhen Zhen, Hai Wang, Yandi Zhang, Yandi Zhang, C.-Y. Hu, C.-Y. Hu, Jin Ma, Zhi-Yong Li, Jia Song, Jin-xin Liu, L. Peng, Yang Liu, Q. Ning, Zheng-xiang Liu (2015)
Interaction of thymic stromal lymphopoietin, IL‐33, and their receptors in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polypsAllergy, 70
J. Sommer, K. Schäfer, H. Omran, H. Olbrich, J. Wallmeier, A. Blum, K. Hörmann, B. Stuck (2011)
ENT manifestations in patients with primary ciliary dyskinesia: prevalence and significance of otorhinolaryngologic co-morbiditiesEuropean Archives of Oto-Rhino-Laryngology, 268
M. Schubert (2000)
Medical treatment of allergic fungal sinusitis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 85 2
JD Kerrebijn, RM Poublon, SE Overbeek (1992)
Nasal and paranasal disease in adult cystic fibrosis patients.The European respiratory journal, 5 10
J. Kennedy, L. Borish (2013)
Chronic rhinosinusitis and antibiotics: The good, the bad, and the ugly, 27
P. Gevaert, L. Calus, T. Zele, Katrien Blomme, N. Ruyck, W. Bauters, P. Hellings, G. Brusselle, D. Bacquer, P. Cauwenberge, C. Bachert (2012)
Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma.The Journal of allergy and clinical immunology, 131 1
J. Rodríguez-Jiménez, Fernanda Moreno-Paz, L. Teran, Eduardo Guaní-Guerra (2018)
Aspirin exacerbated respiratory disease: Current topics and trends.Respiratory medicine, 135
S. Shahid (2012)
Rhinosinusitis in ChildrenISRN Otolaryngology, 2012
R. Cepero, Richard Smith, F. Catlin, K. Bressler, G. Furuta, K. Shandera (1987)
Cystic Fibrosis—An Otolaryngologic PerspectiveOtolaryngology-Head and Neck Surgery, 97
M. Slim, D. Dick, K. Trimble, G. Mckee (2016)
Paediatric nasal polyps in cystic fibrosisBMJ Case Reports, 2016
D. Beswick, A. Messner, P. Hwang (2017)
Pediatric Chronic Rhinosinusitis Management in Rhinologists and Pediatric OtolaryngologistsAnnals of Otology, Rhinology & Laryngology, 126
M. Castro, S. Mathur, F. Hargreave, L. Boulet, F. Xie, James Young, H. Wilkins, T. Henkel, Parameswaran Nair (2011)
Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study.American journal of respiratory and critical care medicine, 184 10
G. Berger, T. Kogan, M. Paker, Sivan Berger‐Achituv, Y. Ebner (2011)
Pediatric Chronic Rhinosinusitis HistopathologyOtolaryngology–Head and Neck Surgery, 144
I. Brook (2017)
The role of antibiotics in pediatric chronic rhinosinusitisLaryngoscope Investigative Otolaryngology, 2
F. Baroody, Samantha Mucha, M. Detineo, R. Naclerio (2008)
Nasal challenge with allergen leads to maxillary sinus inflammation.The Journal of allergy and clinical immunology, 121 5
S. Vandenberg, Diane Heatley (1997)
Efficacy of adenoidectomy in relieving symptoms of chronic sinusitis in children.Archives of otolaryngology--head & neck surgery, 123 7
C. Bachert, P. Gevaert, P. Hellings (2017)
Biotherapeutics in Chronic Rhinosinusitis with and without Nasal Polyps.The journal of allergy and clinical immunology. In practice, 5 6
D. Stevenson, A. Szczeklik (2006)
Clinical and pathologic perspectives on aspirin sensitivity and asthma.The Journal of allergy and clinical immunology, 118 4
N. Bhattacharyya (2010)
The Role of CT and MRI in the Diagnosis of Chronic RhinosinusitisCurrent Allergy and Asthma Reports, 10
A. Rose, B. Thorp, A. Zanation, C. Ebert (2013)
Chronic rhinosinusitis in children.Pediatric clinics of North America, 60 4
D. Hamilos (2015)
Pediatric Chronic RhinosinusitisAmerican Journal of Rhinology & Allergy, 29
S. Ghadersohi, B. Tan (2017)
Contemporary Pharmacotherapy for Allergic Rhinitis and Chronic Rhinosinusitis.Otolaryngologic clinics of North America, 50 6
C. Bachert, A. Sousa, V. Lund, G. Scadding, P. Gevaert, S. Nasser, S. Durham, M. Cornet, H. Kariyawasam, J. Gilbert, D. Austin, A. Maxwell, R. Marshall, W. Fokkens (2017)
Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trialThe Journal of Allergy and Clinical Immunology, 140
S. Payne, L. Borish, J. Steinke (2011)
Genetics and phenotyping in chronic sinusitis.The Journal of allergy and clinical immunology, 128 4
G. Shapiro (1985)
Role of allergy in sinusitisThe Pediatric Infectious Disease Journal, 4
T. Marom, Pedro Alvarez, K. Jennings, J. Patel, D. Mccormick, T. Chonmaitree (2014)
Acute Bacterial Sinusitis Complicating Viral Upper Respiratory Tract Infection in Young ChildrenOtolaryngology–Head and Neck Surgery, 151
M. Lawrence, Thamiris Palacios‐Kibler, L. Workman, Alexander Schuyler, J. Steinke, S. Payne, E. McGowan, J. Patrie, R. Fuleihan, K. Sullivan, P. Lugar, Camellia Hernandez, D. Beakes, J. Verbsky, T. Platts-Mills, C. Cunningham-Rundles, J. Routes, L. Borish (2018)
Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID)Journal of Clinical Immunology, 38
Samuel Collins, W. Walker, J. Lucas (2014)
Genetic Testing in the Diagnosis of Primary Ciliary Dyskinesia: State-of-the-Art and Future PerspectivesJournal of Clinical Medicine, 3
Gary Rachelefsky, M. Goldberg, R. Katz, G. Boris, M. Gyepes, M. Shapiro, Mickey Mr, Sydney Finegold, Sheldon Siegel (1978)
Sinus disease in children with respiratory allergy.The Journal of allergy and clinical immunology, 61 5
F. Baroody, C. Hughes, P. McDowell, R. Hruban, S. Zinreich, R. Naclerio, R. Naclerio (1995)
Eosinophilia in chronic childhood sinusitis.Archives of otolaryngology--head & neck surgery, 121 12
G. Shapiro, F. Virant, C. Furukawa, W. Pierson, Bierman Cw (1991)
Immunologic defects in patients with refractory sinusitis.Pediatrics, 87 3
A. Halderman, Laura Tully (2017)
The Role of Allergy in Chronic Rhinosinusitis.Otolaryngologic clinics of North America, 50 6
Z. Soler, J. Rosenbloom, D. Skarada, M. Gutman, Mark Hoy, S. Nguyen (2016)
Prospective, multicenter evaluation of balloon sinus dilation for treatment of pediatric chronic rhinosinusitisInternational Forum of Allergy & Rhinology, 7
K. Oomen, M. April (2012)
Sinonasal Manifestations in Cystic FibrosisInternational Journal of Otolaryngology, 2012
Brent Uren, A. Psaltis, P. Wormald (2008)
Nasal Lavage With Mupirocin for the Treatment of Surgically Recalcitrant Chronic RhinosinusitisThe Laryngoscope, 118
R. Tandon, C. Derkay (2003)
Contemporary management of rhinosinusitis and cystic fibrosisCurrent Opinion in Otolaryngology & Head and Neck Surgery, 11
Leen Vanlerberghe, Sander Joniau, Mark Jorissen (2006)
The prevalence of humoral immunodeficiency in refractory rhinosinusitis: a retrospective analysis.B-ENT, 2 4
A. Sedaghat, W. Phipatanakul, M. Cunningham (2014)
Prevalence of and associations with allergic rhinitis in children with chronic rhinosinusitis.International journal of pediatric otorhinolaryngology, 78 2
A. Sedaghat, W. Phipatanakul, M. Cunningham (2013)
Atopy and the development of chronic rhinosinusitis in children with allergic rhinitis.The journal of allergy and clinical immunology. In practice, 1 6
L. Cox, H. Nelson, R. Lockey, Christopher Calabria, T. Chacko, I. Finegold, Michael Nelson, R. Weber, D. Bernstein, J. Blessing-Moore, D. Khan, D. Lang, R. Nicklas, J. Oppenheimer, J. Portnoy, C. Randolph, D. Schuller, S. Spector, S. Tilles, D. Wallace (2007)
Allergen immunotherapy: a practice parameter third update.The Journal of allergy and clinical immunology, 127 1 Suppl
Purpose of Review Pediatric chronic rhinosinusitis (CRS) is a common disorder that carries significant morbidity. The diagnosis requires sinus symptoms that persist despite standard medical therapy greater than 3 months. Viral infections, allergies, and anatomic differences in children lead to chronic obstruction of the osteomeatal complex. Recent Findings Chronic rhinosinusitis as a diagnosis is a conglomeration of multiple phenotypes and endotypes. As such, the diagnosis and management are complex. New survey studies provide some consensus on prevalence and management of this disease in children. Summary In this review, we highlight the differential diagnosis of pediatric CRS, including non-eosinophilic/infectious variants, eosinophilic variants with and without nasal polyps, allergic fungal sinusitis, aspirin-exacerbated respiratory disease, primary immunodeficiency, and disorders of mucociliary clearance. Further, we detail treatment options that should be considered. Finally, we feature emerging potential treatment options of CRS, including anti-immunoglobulin E, interleukin-5, and interleukin-4 receptor alpha subunit. . . . . Keywords Pediatric chronic rhinosinusitis Osteomeatal complex Nasal polyps Treatment of pediatric chronic rhinosinusitis Mucociliary clearance Monoclonal antibodies Introduction purulence or discolored postnasal discharge, or fever) or one major and two minor criteria (halitosis, dental pain, fatigue, Rhinosinusitis is a common disorder involving inflammation cough, ear pain, ear pressure, or
Current Allergy and Asthma Reports – Springer Journals
Published: May 29, 2018
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