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Chlorhexidine Allergy: On the Rise and Often Overlooked

Chlorhexidine Allergy: On the Rise and Often Overlooked Purpose of Review In recent years, the risk of allergy to chlorhexidine is increasingly recognised. In this review, we discuss why the allergy is so easily overlooked and point out several preventative initiatives that can minimise the risk of both chlorhexidine sensitisation and allergy development and accidental re-exposure in patients with chlorhexidine allergy. Testing for chlorhexidine allergy is also discussed. Recent Findings Numerous reports have been published from many different specialties. Symptoms range from mild skin symptoms to life-threatening anaphylaxis. Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Recently, it was found that both skin prick testing and specific IgE have high sensitivities and specificities. Summary This review gives an overview of chlorhexidine allergy with a special focus on preventative initiatives and testing. . . . . . Keywords Chlorhexidine Chlorhexidine allergy Skin testing Specific IgE Perioperative allergy Allergy testing Introduction fact that chlorhexidine is used in many different formulations, making exposure difficult to avoid even when an allergy has Chlorhexidine is an effective antiseptic used in the health care been confirmed [5••]. sector and in private homes all over the world (Fig. 1). In high Chlorhexidine can cause both immediate type (type I) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

Chlorhexidine Allergy: On the Rise and Often Overlooked

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References (72)

Publisher
Springer Journals
Copyright
Copyright © 2019 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Allergology
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-019-0858-2
Publisher site
See Article on Publisher Site

Abstract

Purpose of Review In recent years, the risk of allergy to chlorhexidine is increasingly recognised. In this review, we discuss why the allergy is so easily overlooked and point out several preventative initiatives that can minimise the risk of both chlorhexidine sensitisation and allergy development and accidental re-exposure in patients with chlorhexidine allergy. Testing for chlorhexidine allergy is also discussed. Recent Findings Numerous reports have been published from many different specialties. Symptoms range from mild skin symptoms to life-threatening anaphylaxis. Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Recently, it was found that both skin prick testing and specific IgE have high sensitivities and specificities. Summary This review gives an overview of chlorhexidine allergy with a special focus on preventative initiatives and testing. . . . . . Keywords Chlorhexidine Chlorhexidine allergy Skin testing Specific IgE Perioperative allergy Allergy testing Introduction fact that chlorhexidine is used in many different formulations, making exposure difficult to avoid even when an allergy has Chlorhexidine is an effective antiseptic used in the health care been confirmed [5••]. sector and in private homes all over the world (Fig. 1). In high Chlorhexidine can cause both immediate type (type I)

Journal

Current Allergy and Asthma Reports – Springer Journals

Published: Mar 14, 2019

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