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- Publisher
- Springer Journals
- Copyright
- Copyright © 2011 by Springer-Verlag London Limited
- Subject
- Medicine & Public Health; Pathology; Oncology; Hematology
- eISSN
- 1618-565X
- DOI
- 10.1007/s00580-011-1292-6
- Publisher site
- See Article on Publisher Site
Abstract
Iron is an important nutrient for all living systems. Bacteria have developed multiple mechanisms to obtain iron from the host. Aeromonas salmonicida subsp. salmonicida produces catechol-type siderophore under iron starvation conditions. This study attempted to characterize and ascertain the role of a siderophore ABC transporter protein AsbJ in siderophore transporter system in this bacterial pathogen. Prediction of protein domains was carried out, and deleted asbJ gene mutant strain was constructed. Results showed that this protein contains special domain related to permease and ATP-binding protein, and it is essential for the siderophore transport process in this bacterial fish pathogen.
Journal
Comparative Clinical Pathology – Springer Journals
Published: Jul 26, 2011