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Central Nervous System Germ Cell Tumors

Central Nervous System Germ Cell Tumors Primary central nervous system (CNS) germinoma is readily curable with relatively large volume/high dose radiotherapy but the late effects of treatment may alter neurocognitive functioning and quality of life. Prior studies have associated radiation therapy with deficits in the domains of intelligence, attention, memory, and psychomotor processing speed, with risk factors including young age at irradiation and increased irradiation volume and dosage level. Furthermore, cranial irradiation may also lead to diminished height, neuroendocrine dysfunction, and hearing loss. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cancer Springer Journals

Central Nervous System Germ Cell Tumors

American Journal of Cancer , Volume 3 (1) – Aug 10, 2012

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References (61)

Publisher
Springer Journals
Copyright
Copyright © 2004 by Adis Data Information BV
Subject
Pharmacy; Pharmacy
ISSN
1175-6357
DOI
10.2165/00024669-200403010-00004
Publisher site
See Article on Publisher Site

Abstract

Primary central nervous system (CNS) germinoma is readily curable with relatively large volume/high dose radiotherapy but the late effects of treatment may alter neurocognitive functioning and quality of life. Prior studies have associated radiation therapy with deficits in the domains of intelligence, attention, memory, and psychomotor processing speed, with risk factors including young age at irradiation and increased irradiation volume and dosage level. Furthermore, cranial irradiation may also lead to diminished height, neuroendocrine dysfunction, and hearing loss.

Journal

American Journal of CancerSpringer Journals

Published: Aug 10, 2012

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