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Cell and biomolecular mechanics in silico

Cell and biomolecular mechanics in silico Recent developments in computational cell and biomolecular mechanics have provided valuable insights into the mechanical properties of cells, subcellular components and biomolecules, while simultaneously complementing new experimental techniques used for deciphering the structure–function paradigm in living cells. These computational approaches have direct implications in understanding the state of human health and the progress of disease and can therefore aid immensely in the diagnosis and treatment of diseases. We provide an overview of the computational approaches that are currently used in understanding various aspects of cell and bimolecular mechanics. Our emphasis is on state-of-the-art techniques and the progress made in addressing key challenges in biomechanics. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Materials Springer Journals

Cell and biomolecular mechanics in silico

Nature Materials , Volume 7 (1) – Dec 9, 2007

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References (124)

Publisher
Springer Journals
Copyright
Copyright © 2008 by Nature Publishing Group
Subject
Materials Science; Materials Science, general; Optical and Electronic Materials; Biomaterials; Nanotechnology; Condensed Matter Physics
ISSN
1476-1122
eISSN
1476-4660
DOI
10.1038/nmat2040
Publisher site
See Article on Publisher Site

Abstract

Recent developments in computational cell and biomolecular mechanics have provided valuable insights into the mechanical properties of cells, subcellular components and biomolecules, while simultaneously complementing new experimental techniques used for deciphering the structure–function paradigm in living cells. These computational approaches have direct implications in understanding the state of human health and the progress of disease and can therefore aid immensely in the diagnosis and treatment of diseases. We provide an overview of the computational approaches that are currently used in understanding various aspects of cell and bimolecular mechanics. Our emphasis is on state-of-the-art techniques and the progress made in addressing key challenges in biomechanics.

Journal

Nature MaterialsSpringer Journals

Published: Dec 9, 2007

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