Abstract
A subpopulation of cardiac-resident macrophages protect the heart against sepsis-induced cardiomyopathy by scavenging dysfunctional mitochondria ejected from cardiomyocytes; modulation or administration of these macrophages might be a potential therapeutic strategy.
Kai Zhang, Yang-Yang Wang, Shiyu Chen, Jiali Mao, Yue Jin, Hui Ye, Yan Zhang, Xiwang Liu, Chenchen Gong, Xuejun Cheng, Xiaoli Huang, A. Hoeft, Qixing Chen, Xuekun Li, X. Fang (2023)
TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocyte homeostasisNature Metabolism, 5
A subpopulation of cardiac-resident macrophages protect the heart against sepsis-induced cardiomyopathy by scavenging dysfunctional mitochondria ejected from cardiomyocytes; modulation or administration of these macrophages might be a potential therapeutic strategy.
Nature Reviews Cardiology – Springer Journals
Published: Mar 1, 2023
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