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Cancer Detection with Digital Breast Tomosynthesis

Cancer Detection with Digital Breast Tomosynthesis Purpose of ReviewTo bring the reader up to date on recent literature on cancer detection with digital breast tomosynthesis (DBT).Recent FindingsMany early landmark trials have recently published follow-up studies comparing DBT and synthesized DBT (SM + DBT) to digital mammography (DM). Recent work has also focused on interval cancers and biological characteristics of DBT cancers in efforts to assess the impact of cancer detection with DBT.SummaryConsistent increases in cancer detection and overall reductions in recall rates are observed with DBT and maintained with SM + DBT. Studies on interval cancers are underpowered to show significant differences; however, rates are similar or decreased with DBT vs. DM. DBT-detected cancers are more often invasive, but smaller, with less aggressive profiles compared to DM cancers. Future directions will assess whether detection of such cancers will affect morbidity and mortality of breast cancer. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Radiology Reports Springer Journals

Cancer Detection with Digital Breast Tomosynthesis

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References (52)

Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2020
eISSN
2167-4825
DOI
10.1007/s40134-020-00347-1
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewTo bring the reader up to date on recent literature on cancer detection with digital breast tomosynthesis (DBT).Recent FindingsMany early landmark trials have recently published follow-up studies comparing DBT and synthesized DBT (SM + DBT) to digital mammography (DM). Recent work has also focused on interval cancers and biological characteristics of DBT cancers in efforts to assess the impact of cancer detection with DBT.SummaryConsistent increases in cancer detection and overall reductions in recall rates are observed with DBT and maintained with SM + DBT. Studies on interval cancers are underpowered to show significant differences; however, rates are similar or decreased with DBT vs. DM. DBT-detected cancers are more often invasive, but smaller, with less aggressive profiles compared to DM cancers. Future directions will assess whether detection of such cancers will affect morbidity and mortality of breast cancer.

Journal

Current Radiology ReportsSpringer Journals

Published: Mar 28, 2020

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