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Cahn–Hilliard Models for Glial Cells

Cahn–Hilliard Models for Glial Cells Our aim in this paper is to study a Cahn–Hilliard model with a symport term. This equation is proposed to model some energy mechanisms (e.g., lactate) in glial cells. The main difficulty is to prove the existence of a biologically relevant solution. This is achieved by considering a modified equation and taking a logarithmic nonlinear term. A second difficulty is to prove additional regularity on the solutions which is essential to prove a strict separation from the pure states 0 and 1 in one and two space dimensions. We also consider a second model, based on the Cahn–Hilliard–Oono equation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Mathematics and Optimization Springer Journals

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References (34)

Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2020
ISSN
0095-4616
eISSN
1432-0606
DOI
10.1007/s00245-020-09696-x
Publisher site
See Article on Publisher Site

Abstract

Our aim in this paper is to study a Cahn–Hilliard model with a symport term. This equation is proposed to model some energy mechanisms (e.g., lactate) in glial cells. The main difficulty is to prove the existence of a biologically relevant solution. This is achieved by considering a modified equation and taking a logarithmic nonlinear term. A second difficulty is to prove additional regularity on the solutions which is essential to prove a strict separation from the pure states 0 and 1 in one and two space dimensions. We also consider a second model, based on the Cahn–Hilliard–Oono equation.

Journal

Applied Mathematics and OptimizationSpringer Journals

Published: Oct 1, 2021

Keywords: Cahn–Hilliard equation; Cahn–Hilliard–Oono equation; Symport term; Logarithmic nonlinear term; Existence; Regularity; Strict separation; 35K55; 35B45; 35Q92

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