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C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment?

C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment? Cardiovascular Drugs and Therapy https://doi.org/10.1007/s10557-022-07424-x LE T TER TO  THE   EDITOR C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment? 1 2 2 1 Jinjiao Shan  · Sanlong Liu  · Ying Liu  · Jingguang Zhu Accepted: 29 December 2022 © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023 Dear Editor, with wild type mice. These findings suggest that CHOP Recently, an interesting study entitled “C/EBP Homologous may play a protective role in the hippocampal cell apoptosis Protein (CHOP) Increases TRIB3-Dependent miR-208 and impairment of memory performance [4]. Another study Expression to Potentiate Vascular Smooth Muscle Cell uncovered that CHOP deficiency in mice aggravates acute Proliferation and Migration by Downregulating TIMP3 in pancreatitis and associated lung injury [5]. To sum up, Atherosclerosis” was published in Cardiovascular Drugs and inhibition of CHOP has a deleterious effect on many diseases, Therapy [1]. We congratulate the authors and would like to including heart disease. discuss some points about the role of CHOP on atherosclerosis. In conclusion, CHOP played a crucial role in atherosclero- In this article, the authors found that CHOP potentiated sis, but its role and specific mechanism remain controversial. vascular smooth muscle cells (VSMCs) proliferation and More basic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cardiovascular Drugs and Therapy Springer Journals

C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment?

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C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment?

Abstract

Cardiovascular Drugs and Therapy https://doi.org/10.1007/s10557-022-07424-x LE T TER TO  THE   EDITOR C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment? 1 2 2 1 Jinjiao Shan  · Sanlong Liu  · Ying Liu  · Jingguang Zhu Accepted: 29 December 2022 © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023 Dear Editor, with wild...
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References (5)

Publisher
Springer Journals
Copyright
Copyright © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023
ISSN
0920-3206
eISSN
1573-7241
DOI
10.1007/s10557-022-07424-x
Publisher site
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Abstract

Cardiovascular Drugs and Therapy https://doi.org/10.1007/s10557-022-07424-x LE T TER TO  THE   EDITOR C/EBP Homologous Protein: A Potential Therapeutic Target for Atherosclerosis Treatment? 1 2 2 1 Jinjiao Shan  · Sanlong Liu  · Ying Liu  · Jingguang Zhu Accepted: 29 December 2022 © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023 Dear Editor, with wild type mice. These findings suggest that CHOP Recently, an interesting study entitled “C/EBP Homologous may play a protective role in the hippocampal cell apoptosis Protein (CHOP) Increases TRIB3-Dependent miR-208 and impairment of memory performance [4]. Another study Expression to Potentiate Vascular Smooth Muscle Cell uncovered that CHOP deficiency in mice aggravates acute Proliferation and Migration by Downregulating TIMP3 in pancreatitis and associated lung injury [5]. To sum up, Atherosclerosis” was published in Cardiovascular Drugs and inhibition of CHOP has a deleterious effect on many diseases, Therapy [1]. We congratulate the authors and would like to including heart disease. discuss some points about the role of CHOP on atherosclerosis. In conclusion, CHOP played a crucial role in atherosclero- In this article, the authors found that CHOP potentiated sis, but its role and specific mechanism remain controversial. vascular smooth muscle cells (VSMCs) proliferation and More basic

Journal

Cardiovascular Drugs and Therapy – Springer Journals

Published: Jan 16, 2023

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