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Breast Cancer Disparities Related to Young Age at Diagnosis

Breast Cancer Disparities Related to Young Age at Diagnosis Purpose of ReviewDespite being uncommon, breast cancer at a young age correlates with worse outcomes. Several aspects of a breast cancer diagnosis may affect young and older patients differently, including biology, genetic predisposition, fertility concerns, and psychosocial outcomes. Understanding these differences is critical to providing tailored, high-quality care to young patients.Recent FindingsYoung women with breast cancer are less likely to have early stage at presentation and more likely to have tumors with aggressive characteristics. Genetic mutations predisposing to breast cancer are more common. Due to their life stage, young women face concerns regarding fertility and pregnancy and are at higher risk for psychosocial distress.SummaryRecent clinical trials in the adjuvant setting have provided insight on the optimal treatment for young patients. Multiple other studies have outlined the psychosocial impact of breast cancer in young patients, helping to understand their unique challenges. However, there is still need for further research, including around interventions, to address clinical and social concerns specific to young patients. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Breast Cancer Reports Springer Journals

Breast Cancer Disparities Related to Young Age at Diagnosis

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Publisher
Springer Journals
Copyright
Copyright © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
ISSN
1943-4588
eISSN
1943-4596
DOI
10.1007/s12609-022-00459-x
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewDespite being uncommon, breast cancer at a young age correlates with worse outcomes. Several aspects of a breast cancer diagnosis may affect young and older patients differently, including biology, genetic predisposition, fertility concerns, and psychosocial outcomes. Understanding these differences is critical to providing tailored, high-quality care to young patients.Recent FindingsYoung women with breast cancer are less likely to have early stage at presentation and more likely to have tumors with aggressive characteristics. Genetic mutations predisposing to breast cancer are more common. Due to their life stage, young women face concerns regarding fertility and pregnancy and are at higher risk for psychosocial distress.SummaryRecent clinical trials in the adjuvant setting have provided insight on the optimal treatment for young patients. Multiple other studies have outlined the psychosocial impact of breast cancer in young patients, helping to understand their unique challenges. However, there is still need for further research, including around interventions, to address clinical and social concerns specific to young patients.

Journal

Current Breast Cancer ReportsSpringer Journals

Published: Aug 4, 2022

Keywords: Breast Cancer; Young Age; Disparities

References