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Biomaterials as Antigen Delivery Carrier for Cancer Immunotherapy

Biomaterials as Antigen Delivery Carrier for Cancer Immunotherapy Since immunotherapy provides an opportunity to treat metastatic and disseminated tumors, it has become a major treatment strategy for cancer. However, current cancer immunotherapeutics have often exhibited insufficient practical outcomes, primarily attributed to inefficient delivery of tumor-associated antigens to elicit anticancer immunity. To achieve improved therapeutic efficacy, numerous efforts have been made to harness biomaterials for the targeted or sustained delivery of tumor-associated antigens to antigen-presenting cells. In this review, we highlight recent advances in the development of biomaterials to deliver tumor-associated antigens and their therapeutic potential for cancer treatment.[graphic not available: see fulltext] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Macromolecular Research Springer Journals

Biomaterials as Antigen Delivery Carrier for Cancer Immunotherapy

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References (79)

Publisher
Springer Journals
Copyright
Copyright © The Polymer Society of Korea and Springer 2021
ISSN
1598-5032
eISSN
2092-7673
DOI
10.1007/s13233-021-9095-3
Publisher site
See Article on Publisher Site

Abstract

Since immunotherapy provides an opportunity to treat metastatic and disseminated tumors, it has become a major treatment strategy for cancer. However, current cancer immunotherapeutics have often exhibited insufficient practical outcomes, primarily attributed to inefficient delivery of tumor-associated antigens to elicit anticancer immunity. To achieve improved therapeutic efficacy, numerous efforts have been made to harness biomaterials for the targeted or sustained delivery of tumor-associated antigens to antigen-presenting cells. In this review, we highlight recent advances in the development of biomaterials to deliver tumor-associated antigens and their therapeutic potential for cancer treatment.[graphic not available: see fulltext]

Journal

Macromolecular ResearchSpringer Journals

Published: Dec 1, 2021

Keywords: biomaterials; antigen delivery; cancer immunotherapy

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