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Bevacizumab

Bevacizumab The tolerability profile of bevacizumab was generally acceptable in clinical trials in patients with advanced colorectal cancer, breast cancer, or NSCLC. In pooled analysis, the most common adverse events of any severity in patients receiving bevacizumab were asthenia, pain, abdominal pain, headache, hypertension, diarrhea, nausea, vomiting, anorexia, stomatitis, constipation, upper respiratory infection, epistaxis, dyspnea, exfoliative dermatitis, and proteinuria. Most adverse events were mild to moderate in severity, and events such as hypertension, hemorrhage, or proteinuria were clinically manageable. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cancer Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2006 by Adis Data Information BV
Subject
Pharmacy; Pharmacy
ISSN
1175-6357
DOI
10.2165/00024669-200605010-00009
Publisher site
See Article on Publisher Site

Abstract

The tolerability profile of bevacizumab was generally acceptable in clinical trials in patients with advanced colorectal cancer, breast cancer, or NSCLC. In pooled analysis, the most common adverse events of any severity in patients receiving bevacizumab were asthenia, pain, abdominal pain, headache, hypertension, diarrhea, nausea, vomiting, anorexia, stomatitis, constipation, upper respiratory infection, epistaxis, dyspnea, exfoliative dermatitis, and proteinuria. Most adverse events were mild to moderate in severity, and events such as hypertension, hemorrhage, or proteinuria were clinically manageable.

Journal

American Journal of CancerSpringer Journals

Published: Aug 10, 2012

References