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Backbone 1H, 13C and 15N resonance assignments of human vaccinia-related kinase 1 (VRK1)

Backbone 1H, 13C and 15N resonance assignments of human vaccinia-related kinase 1 (VRK1) Vaccinia-related kinase 1 (VRK1) is one of the mitotic kinases which play key roles in cell cycle control and chromatin modifications. To understand the biological role of the kinase and gain insights into its catalytic mechanism, we performed NMR assignments of catalytically active form of VRK1 with 361 amino acids residues. Here, we present the backbone NMR resonance assignments of the kinase. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Biomolecular NMR Assignments Springer Journals

Backbone 1H, 13C and 15N resonance assignments of human vaccinia-related kinase 1 (VRK1)

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Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media Dordrecht 2012
Subject
Physics; Biophysics and Biological Physics; Polymer Sciences; Biochemistry, general
ISSN
1874-2718
eISSN
1874-270X
DOI
10.1007/s12104-012-9446-2
pmid
23212441
Publisher site
See Article on Publisher Site

Abstract

Vaccinia-related kinase 1 (VRK1) is one of the mitotic kinases which play key roles in cell cycle control and chromatin modifications. To understand the biological role of the kinase and gain insights into its catalytic mechanism, we performed NMR assignments of catalytically active form of VRK1 with 361 amino acids residues. Here, we present the backbone NMR resonance assignments of the kinase.

Journal

Biomolecular NMR AssignmentsSpringer Journals

Published: Apr 1, 2014

Keywords: VRK1; NMR; Protein kinase; Mitotic kinase; Cell cycle regulation; Chromatin modification

References