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Curr Breast Cancer Rep (2011) 3:75–78 DOI 10.1007/s12609-011-0043-7 CLINICAL TRIAL REPORT Axillary Dissection in Women with Invasive Breast Cancer and Sentinel Node Metastasis Kelly K. Hunt Published online: 24 March 2011 # Springer Science+Business Media, LLC 2011 Giuliano AE, Hunt KK, Ballman KV, et al. Axillary nodal disease at the time of initial surgical treatment of the dissection vs no axillary dissection in women with invasive primary tumor had any impact on survival compared with breast cancer and sentinel node metastasis: a randomized patients who did not have lymph node surgery or received clinical trial. JAMA 2011;305:569–575. radiation. Patients enrolled in B-04 did not receive adjuvant systemic therapy and the mean tumor size was 3.3 cm Rating: among node-negative patients. The results were published Of significant importance. in 1977 and showed no difference in survival between the treatment groups [1]. A more recent publication from the Introduction: Axillary lymph node dissection (ALND) has NSABP B-04 trial demonstrated that patients treated been an integral component of the surgical management of without axillary surgery, despite the presence of axillary breast cancer patients for decades. The routine removal of metastases, had no diminution in either regional control or axillary lymph nodes serves
Current Breast Cancer Reports – Springer Journals
Published: Mar 24, 2011
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