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Asymptotics on Semiparametric Analysis of Multivariate Failure Time Data Under the Additive Hazards Model

Asymptotics on Semiparametric Analysis of Multivariate Failure Time Data Under the Additive... Many survival studies record the times to two or more distinct failures on each subject. The failures may be events of different natures or may be repetitions of the same kind of event. In this article, we consider the regression analysis of such multivariate failure time data under the additive hazards model. Simple weighted estimating functions for the regression parameters are proposed, and asymptotic distribution theory of the resulting estimators are derived. In addition, a class of generalized Wald and generalized score statistics for hypothesis testing and model selection are presented, and the asymptotic properties of these statistics are examined. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Mathematicae Applicatae Sinica Springer Journals

Asymptotics on Semiparametric Analysis of Multivariate Failure Time Data Under the Additive Hazards Model

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Publisher
Springer Journals
Copyright
Copyright © 2005 by Springer-Verlag Berlin Heidelberg
Subject
Mathematics; Applications of Mathematics; Math Applications in Computer Science; Theoretical, Mathematical and Computational Physics
ISSN
0168-9673
eISSN
1618-3932
DOI
10.1007/s10255-005-0232-0
Publisher site
See Article on Publisher Site

Abstract

Many survival studies record the times to two or more distinct failures on each subject. The failures may be events of different natures or may be repetitions of the same kind of event. In this article, we consider the regression analysis of such multivariate failure time data under the additive hazards model. Simple weighted estimating functions for the regression parameters are proposed, and asymptotic distribution theory of the resulting estimators are derived. In addition, a class of generalized Wald and generalized score statistics for hypothesis testing and model selection are presented, and the asymptotic properties of these statistics are examined.

Journal

Acta Mathematicae Applicatae SinicaSpringer Journals

Published: Jan 1, 2005

References