Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Assignments of human integrin α1I domain in the apo and Mg2+ bound states

Assignments of human integrin α1I domain in the apo and Mg2+ bound states The α1β1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its α-subunit called the αI domain (αI). αI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human α1I and the chemical shift changes resulting from metal coordination. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Biomolecular NMR Assignments Springer Journals

Assignments of human integrin α1I domain in the apo and Mg2+ bound states

Loading next page...
 
/lp/springer-journals/assignments-of-human-integrin-1i-domain-in-the-apo-and-mg2-bound-G3BK33tM6p
Publisher
Springer Journals
Copyright
Copyright © 2013 by Springer Science+Business Media Dordrecht
Subject
Physics; Biophysics and Biological Physics; Polymer Sciences; Biochemistry, general
ISSN
1874-2718
eISSN
1874-270X
DOI
10.1007/s12104-013-9465-7
pmid
23339031
Publisher site
See Article on Publisher Site

Abstract

The α1β1 integrin receptor binds to its main extracellular ligand, collagen, through an inserted domain in its α-subunit called the αI domain (αI). αI contains a metal binding site that allows collagen to coordinate to the domain through a divalent metal ion. Here we report the backbone assignments of the apo and Mg2+ bound state of the isolated human α1I and the chemical shift changes resulting from metal coordination.

Journal

Biomolecular NMR AssignmentsSpringer Journals

Published: Jan 22, 2013

References