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Amphibian regeneration and cellular heterochrony

Amphibian regeneration and cellular heterochrony It is posited that the initiating event of amphibian regeneration of a limb, is ‘retrodifferentiation’* of what are to become the developing cells of the blastema. These cells reiterate a larval or premetamorphic ontogenic repertoire, induced by elevated levels of prolactin with adequate innervation. Subsequent redifferentiation of the blastema cells occurs, controlled by thyroxine and innervation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Biotheoretica Springer Journals

Amphibian regeneration and cellular heterochrony

Acta Biotheoretica , Volume 31 (3) – Jun 2, 2005

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References (18)

Publisher
Springer Journals
Copyright
Copyright
Subject
Philosophy; Philosophy of Biology; Evolutionary Biology
ISSN
0001-5342
eISSN
1572-8358
DOI
10.1007/BF01857240
Publisher site
See Article on Publisher Site

Abstract

It is posited that the initiating event of amphibian regeneration of a limb, is ‘retrodifferentiation’* of what are to become the developing cells of the blastema. These cells reiterate a larval or premetamorphic ontogenic repertoire, induced by elevated levels of prolactin with adequate innervation. Subsequent redifferentiation of the blastema cells occurs, controlled by thyroxine and innervation.

Journal

Acta BiotheoreticaSpringer Journals

Published: Jun 2, 2005

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