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Albumin therapy for hepatic encephalopathy: current evidence and controversies

Albumin therapy for hepatic encephalopathy: current evidence and controversies Hepatic encephalopathy (HE) is a common complication that occurs in 16–21% of end-stage cirrhosis patients. Emerging evidence suggests that systemic inflammation and oxidative stress may play a role in the development of HE. Recent understanding on the anti-inflammatory properties of human albumin has led to growing interest of using human albumin for the treatment and prevention of HE among decompensated patients. In this review, we aim to discuss the current evidence and controversies of using human albumin for the treatment and prevention of HE in advanced cirrhosis patients. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Metabolic Brain Disease Springer Journals

Albumin therapy for hepatic encephalopathy: current evidence and controversies

Metabolic Brain Disease , Volume 38 (5) – Jun 1, 2023

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References (35)

Publisher
Springer Journals
Copyright
Copyright © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022
ISSN
0885-7490
eISSN
1573-7365
DOI
10.1007/s11011-022-01002-8
Publisher site
See Article on Publisher Site

Abstract

Hepatic encephalopathy (HE) is a common complication that occurs in 16–21% of end-stage cirrhosis patients. Emerging evidence suggests that systemic inflammation and oxidative stress may play a role in the development of HE. Recent understanding on the anti-inflammatory properties of human albumin has led to growing interest of using human albumin for the treatment and prevention of HE among decompensated patients. In this review, we aim to discuss the current evidence and controversies of using human albumin for the treatment and prevention of HE in advanced cirrhosis patients.

Journal

Metabolic Brain DiseaseSpringer Journals

Published: Jun 1, 2023

Keywords: Albumins; Hepatic encephalopathy; Liver cirrhosis; Mortality

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