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Addition of intranasal glucocorticoids to standard antibiotic therapy for sinusitis

Addition of intranasal glucocorticoids to standard antibiotic therapy for sinusitis James N. Baraniuk, MD Addition of Intranasal Glucocorticoids to Standard Antibiotic Therapy for Sinusitis Meltzer EO, Charous L, Busse WA, et al.: Added relief of 6 or more, at least one moderate or severe symptom, in the treatment of acute recurrent sinusitis with purulent rhinorrhea, and limited coronal CT showing adjunctive mometasone furoate nasal spray. mucosal thickening or air-fluid levels consistent with J Allergy Clin Immunol 2000, 106:630–637. sinusitis. Additional demographic, eosinophil count, IgE, and radioallergosorbent test results were collected. Rating: ••Of outstanding importance. Subjects received 21 days of Augmentin (875 mg twice daily) and either mometasone, 200 μg per nostril twice Introduction: Acute and chronic sinusitis are common daily (800 μg/d total dose), or placebo. No concurrent problems; however, there are significant overlapping symp- medications such as antihistamines, decongestants, ste- toms with allergic and nonallergic rhinitis. The differential roids, or opioids were permitted. Acetaminophen was diagnosis for sinusitis includes viral infections, acute puru- allowed. Subjects scored symptom severity twice daily and lent bacterial rhinosinusitis, inflammation or infection in on day 21 had repeated CT and assessed their global subjects with anatomic obstructions to sinus ostia or aller- improvement. Sample size estimates were 200 per group to gic rhinitis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

Addition of intranasal glucocorticoids to standard antibiotic therapy for sinusitis

Current Allergy and Asthma Reports , Volume 1 (3) – May 25, 2001

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Publisher
Springer Journals
Copyright
Copyright © 2001 by Current Science Inc.
Subject
Medicine & Public Health; Allergology; Pneumology/Respiratory System; Otorhinolaryngology; Infectious Diseases
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-001-0004-8
Publisher site
See Article on Publisher Site

Abstract

James N. Baraniuk, MD Addition of Intranasal Glucocorticoids to Standard Antibiotic Therapy for Sinusitis Meltzer EO, Charous L, Busse WA, et al.: Added relief of 6 or more, at least one moderate or severe symptom, in the treatment of acute recurrent sinusitis with purulent rhinorrhea, and limited coronal CT showing adjunctive mometasone furoate nasal spray. mucosal thickening or air-fluid levels consistent with J Allergy Clin Immunol 2000, 106:630–637. sinusitis. Additional demographic, eosinophil count, IgE, and radioallergosorbent test results were collected. Rating: ••Of outstanding importance. Subjects received 21 days of Augmentin (875 mg twice daily) and either mometasone, 200 μg per nostril twice Introduction: Acute and chronic sinusitis are common daily (800 μg/d total dose), or placebo. No concurrent problems; however, there are significant overlapping symp- medications such as antihistamines, decongestants, ste- toms with allergic and nonallergic rhinitis. The differential roids, or opioids were permitted. Acetaminophen was diagnosis for sinusitis includes viral infections, acute puru- allowed. Subjects scored symptom severity twice daily and lent bacterial rhinosinusitis, inflammation or infection in on day 21 had repeated CT and assessed their global subjects with anatomic obstructions to sinus ostia or aller- improvement. Sample size estimates were 200 per group to gic rhinitis

Journal

Current Allergy and Asthma ReportsSpringer Journals

Published: May 25, 2001

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