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A novel electrochemical sensor for uric acid detection based on PCN/MWCNT

A novel electrochemical sensor for uric acid detection based on PCN/MWCNT A simple, novel electrochemical sensing platform based on porous g-C N (PCN) and multi-walled carbon nanotubes 3 4 (MWCNTs) for the sensitive detection of uric acid (UA) has been proposed. The obtained PCN possessed good biocompatibility and large specific surface area with good dispersion, which was beneficial to electrocatalysis. The introduction of MWCNT as the conducting matrix improved the poor conductivity of PCN. Due to synergistic effect, the redox peak currents of UA substantially enhanced at PCN/MWCNT-modified electrode. The oxidation peak current exhibited linear responses to the concentration of UA in the range from 0.2 to 4 μMand 4to20 μM, and the limit of detection was calculated as 0.139 μM (signal-to-noise ratio of 3 (S/N = 3)). The sensor based on PCN/MWCNT-modified electrode was also successfully applied in human serums and also showed excellent selec- tivity, reproducibility, and stability. This work illustrated that the fabricated electrochemical sensor was promising for analytical applications. . . . Keywords PCN MWCNTs Electrochemical sensor UA Introduction has drawn special attention, thanks to good biocompatibil- ity, excellent chemical stability, and tunable electronic As the most stable allotrope of carbon nitride, graphitic structure [2, 3]. It is widely applied in many related fields, carbon nitride http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Ionics Springer Journals

A novel electrochemical sensor for uric acid detection based on PCN/MWCNT

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References (48)

Publisher
Springer Journals
Copyright
Copyright © 2019 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Chemistry; Electrochemistry; Renewable and Green Energy; Optical and Electronic Materials; Condensed Matter Physics; Energy Storage
ISSN
0947-7047
eISSN
1862-0760
DOI
10.1007/s11581-019-03010-8
Publisher site
See Article on Publisher Site

Abstract

A simple, novel electrochemical sensing platform based on porous g-C N (PCN) and multi-walled carbon nanotubes 3 4 (MWCNTs) for the sensitive detection of uric acid (UA) has been proposed. The obtained PCN possessed good biocompatibility and large specific surface area with good dispersion, which was beneficial to electrocatalysis. The introduction of MWCNT as the conducting matrix improved the poor conductivity of PCN. Due to synergistic effect, the redox peak currents of UA substantially enhanced at PCN/MWCNT-modified electrode. The oxidation peak current exhibited linear responses to the concentration of UA in the range from 0.2 to 4 μMand 4to20 μM, and the limit of detection was calculated as 0.139 μM (signal-to-noise ratio of 3 (S/N = 3)). The sensor based on PCN/MWCNT-modified electrode was also successfully applied in human serums and also showed excellent selec- tivity, reproducibility, and stability. This work illustrated that the fabricated electrochemical sensor was promising for analytical applications. . . . Keywords PCN MWCNTs Electrochemical sensor UA Introduction has drawn special attention, thanks to good biocompatibil- ity, excellent chemical stability, and tunable electronic As the most stable allotrope of carbon nitride, graphitic structure [2, 3]. It is widely applied in many related fields, carbon nitride

Journal

IonicsSpringer Journals

Published: May 17, 2019

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