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A cephalexin-synthesizing hydrolase fromXanthomonas rubrilineans

A cephalexin-synthesizing hydrolase fromXanthomonas rubrilineans The use of peptide hydrolase (EC 3.4.13.1) fromXanthomonas rubrilineans for synthesis of the antibiotic cephalexin from 7-aminodesacetoxycephalosporanic acid was studied. The optimum conditions for production of cephalexin were determined, and the yield exceeded 80%. A method for monitoring the synthesis of this antibiotic by means of a conventional amino acid analyzer is proposed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Biochemistry and Microbiology Springer Journals

A cephalexin-synthesizing hydrolase fromXanthomonas rubrilineans

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References (6)

Publisher
Springer Journals
Copyright
Copyright © 2000 by MAIK “Nauka/Interperiodica”
Subject
Life Sciences; Biochemistry, general; Microbiology; Medical Microbiology
ISSN
0003-6838
eISSN
1608-3024
DOI
10.1007/BF02742576
Publisher site
See Article on Publisher Site

Abstract

The use of peptide hydrolase (EC 3.4.13.1) fromXanthomonas rubrilineans for synthesis of the antibiotic cephalexin from 7-aminodesacetoxycephalosporanic acid was studied. The optimum conditions for production of cephalexin were determined, and the yield exceeded 80%. A method for monitoring the synthesis of this antibiotic by means of a conventional amino acid analyzer is proposed.

Journal

Applied Biochemistry and Microbiology – Springer Journals

Published: Nov 6, 2007

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