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A Case of Giant Advanced Sebaceous Gland Carcinoma

A Case of Giant Advanced Sebaceous Gland Carcinoma Abstract Sebaceous carcinoma is a highly aggressive, potentially lethal tumour arising from the sebaceous glands in the skin. It accounts for 3.2 % of all malignant skin tumours. An advanced case of sebaceous carcinoma with distant metastasis is very rare as most of them present in the periocular area and are easily visible. We present an elderly woman who presented with two large fungating exophytic masses over the right parotid/orbital region and right side of neck. FNAC showed cytological features suggestive of poorly differentiated carcinoma which on histopathological exam confirmed it to be sebaceous carcinoma. Unfortunately the patient succumbed to cardiac arrest before initiation of treatment. This is the largest case of sebaceous gland carcinoma of eyelid reported in the medical literature, confirming the local aggressive behavior of the tumor and highlighting the importance of early diagnosis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Indian Journal of Surgical Oncology Springer Journals

A Case of Giant Advanced Sebaceous Gland Carcinoma

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Publisher
Springer Journals
Copyright
2013 Indian Association of Surgical Oncology
ISSN
0975-7651
eISSN
0976-6952
DOI
10.1007/s13193-013-0254-7
Publisher site
See Article on Publisher Site

Abstract

Abstract Sebaceous carcinoma is a highly aggressive, potentially lethal tumour arising from the sebaceous glands in the skin. It accounts for 3.2 % of all malignant skin tumours. An advanced case of sebaceous carcinoma with distant metastasis is very rare as most of them present in the periocular area and are easily visible. We present an elderly woman who presented with two large fungating exophytic masses over the right parotid/orbital region and right side of neck. FNAC showed cytological features suggestive of poorly differentiated carcinoma which on histopathological exam confirmed it to be sebaceous carcinoma. Unfortunately the patient succumbed to cardiac arrest before initiation of treatment. This is the largest case of sebaceous gland carcinoma of eyelid reported in the medical literature, confirming the local aggressive behavior of the tumor and highlighting the importance of early diagnosis.

Journal

Indian Journal of Surgical Oncology – Springer Journals

Published: Dec 1, 2013

Keywords: surgical oncology; oncology; surgery

References

  • Sebaceous carcinoma of the eyelid: a clinicopathological study
    Z Marlis, CR Hintschich, A Garner
  • Sebaceous carcinoma of the ocular adnexa
    LG Kass, A Hornblass
  • Sebaceous carcinoma of the eyelid and caruncle: Correlation of clinicopathologic features with prognosis
    LE Zimmerman
  • Sebaceous and meibomian carcinomas of the eyelid. Recognition, diagnosis, and management
    JA Khan, JF Doane, AS Grove
  • The management of Meibomian gland carcinoma
    JT Harvey, RL Anderson