Access the full text.
Sign up today, get DeepDyve free for 14 days.
Yang Shen, F. Delaglio, Gabriel Cornilescu, A. Bax (2009)
TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shiftsJournal of Biomolecular NMR, 44
D. Pandey, K. Gerdes (2005)
Toxin–antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotesNucleic Acids Research, 33
K. Winther, K. Gerdes (2012)
Regulation of Enteric vapBC Transcription: Induction by VapC Toxin Dimer-BreakingNucleic Acids Research, 40
M. Sattler, J. Schleucher, C. Griesinger (1999)
Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradientsProgress in Nuclear Magnetic Resonance Spectroscopy, 34
W. Vranken, W. Boucher, T. Stevens, R. Fogh, A. Pajon, M. Llinás, E. Ulrich, J. Markley, J. Ionides, E. Laue (2005)
The CCPN data model for NMR spectroscopy: Development of a software pipelineProteins: Structure, 59
L. Buts, J. Lah, M. Dao‐Thi, L. Wyns, R. Loris (2005)
Toxin-antitoxin modules as bacterial metabolic stress managers.Trends in biochemical sciences, 30 12
R. Magnuson (2007)
Hypothetical Functions of Toxin-Antitoxin SystemsJournal of Bacteriology, 189
D. Wishart, B. Sykes (1994)
The 13C Chemical-Shift Index: A simple method for the identification of protein secondary structure using 13C chemical-shift dataJournal of Biomolecular NMR, 4
Natalie Jonge, A. Garcia-Pino, L. Buts, Sarah Haesaerts, D. Charlier, K. Zangger, L. Wyns, H. Greve, R. Loris (2009)
Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.Molecular cell, 35 2
M. Overgaard, J. Borch, M. Jørgensen, K. Gerdes (2008)
Messenger RNA interferase RelE controls relBE transcription by conditional cooperativityMolecular Microbiology, 69
F. Delaglio, S. Grzesiek, G. Vuister, G. Zhu, John Pfeifer, A. Bax (1995)
NMRPipe: A multidimensional spectral processing system based on UNIX pipesJournal of Biomolecular NMR, 6
M. Arbing, S. Handelman, A. Kuzin, G. Verdon, Chi Wang, M. Su, Francesca Rothenbacher, M. Abashidze, Mohan Liu, J. Hurley, R. Xiao, T. Acton, M. Inouye, G. Montelione, N. Woychik, J. Hunt (2010)
Crystal structures of Phd-Doc, HigA, and YeeU establish multiple evolutionary links between microbial growth-regulating toxin-antitoxin systems.Structure, 18 8
Bruce Johnson (2004)
Using NMRView to visualize and analyze the NMR spectra of macromolecules.Methods in molecular biology, 278
A. Garcia-Pino, Sreeram Balasubramanian, L. Wyns, E. Gazit, H. Greve, R. Magnuson, D. Charlier, N. Nuland, R. Loris (2010)
Allostery and Intrinsic Disorder Mediate Transcription Regulation by Conditional CooperativityCell, 142
K. Gerdes, S. Christensen, A. Løbner‐Olesen (2005)
Prokaryotic toxin–antitoxin stress response lociNature Reviews Microbiology, 3
A. Garcia-Pino, Mikkel Christensen-Dalsgaard, L. Wyns, M. Yarmolinsky, R. Magnuson, K. Gerdes, R. Loris (2008)
Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation*♦Journal of Biological Chemistry, 283
Vivek Anantharaman, L. Aravind (2003)
New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay systemGenome Biology, 4
Toxin–antitoxin (TA) modules in bacteria are involved in pathogenesis, antibiotic stress response, persister formation and programmed cell death. The toxin Doc, from the phd/doc module, blocks protein synthesis by targeting the translation machinery. Despite a large wealth of biophysical and biochemical data on the regulatory aspects of the operon transcription and role of Doc co-activator and co-repressor, little is still know on the molecular basis of Doc toxicity. Structural information about this toxin is only available for its inhibited state bound to the antitoxin Phd. Here we report the 1H, 15N and 13C backbone and side chain chemical shift assignments of the toxin Doc from of bacteriophage P1 (the model protein from this family of TA modules) in its free state. The BMRB accession number is 18899.
Biomolecular NMR Assignments – Springer Journals
Published: Feb 19, 2013
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.