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Nucl Med Mol Imaging (2013) 47:249–256 DOI 10.1007/s13139-013-0224-6 ORIGINAL ARTICLE F-FDG PET in Patients with Primary Systemic Anaplastic Large Cell Lymphoma: Differential Features According to Expression of Anaplastic Lymphoma Kinase Dong Yun Lee & Jong Jin Lee & Jin Yong Kim & Seol Hoon Park & Sun-Young Chae & Shin Kim & Dok Hyun Yoon & Cheolwon Suh & Jooryung Huh & Jin-Sook Ryu Received: 13 June 2013 /Revised: 24 July 2013 /Accepted: 5 August 2013 /Published online: 23 August 2013 Korean Society of Nuclear Medicine 2013 Abstract rate in negative-interim PET was higher than positive-interim Purpose Primary systemic anaplastic large cell lymphoma PET (100 % vs 37.5 %, P =0.02); however, there was no such (ALCL) is divided into two entities according to the expres- difference in ALK-positive ALCL (100 % vs 75 %, P =0.19). sion of anaplastic lymphoma kinase (ALK). We investigated The 3-year progression-free survival (PFS) was not signifi- F-fluorodeoxyglucose positron emission tomography cantly different between ALK-positive and ALK-negative ( F-FDG PET) findings in primary systemic ALCL according ALCL (72.7 % vs 47.6 %, P =0.34). In ALK-negative ALCL, to ALK expression. negative interim and post-therapy PET patients had better 3- Methods Thirty-seven patients who
Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Aug 23, 2013
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