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References (30)
-
M. Fryknäs, Ulrika Wickenberg-Bolin, Hanna Göransson, M. Gustafsson, T. Foukakis, Jia-Jing Lee, U. Landegren, A. Höög, C. Larsson, L. Grimelius, G. Wallin, U. Pettersson, A. Isaksson (2006)
Molecular Markers for Discrimination of Benign and Malignant Follicular Thyroid TumorsTumor Biology, 27
-
Ralf Winzer, C. Schmutzler, Tatjana Jakobs, Regina Ebert, Johann Rendl, Christoph Reiners, Franz Jakob, Josef Köhrle (1998)
Reverse transcriptase-polymerase chain reaction analysis of thyrocyte-relevant genes in fine-needle aspiration biopsies of the human thyroid.Thyroid : official journal of the American Thyroid Association, 8 11
-
D. Parkin, F. Bray, J. Ferlay, P. Pisani (2005)
Global Cancer Statistics, 2002CA: A Cancer Journal for Clinicians, 55
-
(2000)
PAX 8 - PPARgamma 1 fusion oncogene in human thyroid carcinoma -
H. Gharib, J. Goellner, Darwin Johnson (1993)
Fine-needle aspiration cytology of the thyroid. A 12-year experience with 11,000 biopsies.Clinics in laboratory medicine, 13 3
-
Z. Baloch, Seth Fleisher, V. Livolsi, Prabodh Gupta (2002)
Diagnosis of “follicular neoplasm”: A gray zone in thyroid fine‐needle aspiration cytologyDiagnostic Cytopathology, 26
-
H. Gharib (1994)
Fine-needle aspiration biopsy of thyroid nodules: advantages, limitations, and effect.Mayo Clinic proceedings, 69 1
-
Chiara Mazzanti, Chiara Mazzanti, M. Zeiger, Nick Costourous, C. Umbricht, W. Westra, Dañelle Smith, Helina Somervell, G. Bevilacqua, H. Alexander, S. Libutti (2004)
Using gene expression profiling to differentiate benign versus malignant thyroid tumors.Cancer research, 64 8
-
S. Hundahl, I. Fleming, A. Fremgen, H. Menck (1998)
A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985‐1995Cancer, 83
-
L. Cheung, M. Messina, A. Gill, A. Clarkson, D. Learoyd, L. Delbridge, J. Wentworth, J. Philips, R. Clifton-Bligh, B. Robinson (2003)
Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas.The Journal of clinical endocrinology and metabolism, 88 1
-
C. Ravetto, Luigia Colombo, M. Dottorini (2000)
Usefulness of fine‐needle aspiration in the diagnosis of thyroid carcinomaCancer Cytopathology, 90
-
B. Stolf, Mariana Santos, D. Simão, Juan Díaz, E. Cristo, Roberto Hirata, M. Curado, E. Neves, Luiz Kowalski, A. Carvalho (2006)
Class distinction between follicular adenomas and follicular carcinomas of the thyroid gland on the basis of their signature expressionCancer, 106
-
M. Aldred, M. Ginn-Pease, C. Morrison, A. Popkie, O. Gimm, C. Hoang‐Vu, U. Krause, H. Dralle, S. Jhiang, C. Plass, C. Eng (2003)
Caveolin-1 and caveolin-2,together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis.Cancer research, 63 11
-
L. Martins, Sílvia Matsuo, Kátia Ebina, M. Kulcsar, C. Friguglietti, E. Kimura (2002)
Galectin-3 messenger ribonucleic acid and protein are expressed in benign thyroid tumors.The Journal of clinical endocrinology and metabolism, 87 10
-
H. Inohara, Y. Honjo, T. Yoshii, Shiro Akahani, Jun‐ichi Yoshida, K. Hattori, S. Okamoto, Toru Sawada, A. Raz, T. Kubo (1999)
Expression of galectin‐3 in fine‐needle aspirates as a diagnostic marker differentiating benign from malignant thyroid neoplasmsCancer, 85
-
C. Barden, Katherine Shister, Baixin Zhu, G. Guiter, D. Greenblatt, M. Zeiger, T. Fahey (2003)
Classification of follicular thyroid tumors by molecular signature: results of gene profiling.Clinical cancer research : an official journal of the American Association for Cancer Research, 9 5
-
Toru Takano, Akira Miyauchi, F. Matsuzuka, Gang Liu, T. Higashiyama, T. Yokozawa, Kanji Kuma, Nobuyuki Amino (1999)
Preoperative diagnosis of medullary thyroid carcinoma by RT-PCR using RNA extracted from leftover cells within a needle used for fine needle aspiration biopsy.The Journal of clinical endocrinology and metabolism, 84 3
-
A. Marques, C. Espadinha, A. Catarino, S. Moniz, T. Pereira, L. Sobrinho, V. Leite (2002)
Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas.The Journal of clinical endocrinology and metabolism, 87 8
-
Meei Yeung, J. Serpell (2008)
Management of the solitary thyroid nodule.The oncologist, 13 2
-
C. Lubitz, L. Gallagher, David Finley, Baixin Zhu, T. Fahey (2005)
Molecular analysis of minimally invasive follicular carcinomas by gene profiling.Surgery, 138 6
-
J. Goellner, H. Gharib, C. Grant, D. Johnson (1987)
Fine needle aspiration cytology of the thyroid, 1980 to 1986.Acta cytologica, 31 5
-
A. Bartolazzi, A. Gasbarri, M. Papotti, G. Bussolati, T. Lucante, Ashraf Khan, H. Inohara, F. Marandino, F. Orlandi, F. Nardi, A. Vecchione, R. Tecce, O. Larsson (2001)
Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesionsThe Lancet, 357
-
Armando Bartolazzi, Giovanni Bussolati (2006)
Galectin‐3 does not reliably distinguish benign from malignant thyroid neoplasmsHistopathology, 48
-
Anna-Kaarina Järvinen, S. Hautaniemi, H. Edgren, P. Auvinen, J. Saarela, O. Kallioniemi, O. Monni (2004)
Are data from different gene expression microarray platforms comparable?Genomics, 83 6
-
Paul Tan, T. Downey, E. Spitznagel, Pin Xu, Dadin Fu, D. Dimitrov, R. Lempicki, B. Raaka, M. Cam (2003)
Evaluation of gene expression measurements from commercial microarray platforms.Nucleic acids research, 31 19
-
Jianming Zhao, C. Leonard, E. Brunner, E. Gemsenjäger, P. Heitz, B. Odermatt (2006)
Molecular characterization of well-differentiated human thyroid carcinomas by cDNA arrays.International journal of oncology, 29 5
-
T. Fahey (2006)
Genetic Classification of Benign and Malignant Thyroid Follicular Neoplasia Based on a Three-Gene CombinationYearbook of Surgery, 2006
-
S. Chevillard, N. Ugolin, P. Vielh, K. Ory, C. Levalois, Danielle Elliott, G. Clayman, A. El-Naggar (2004)
Gene Expression Profiling of Differentiated Thyroid NeoplasmsClinical Cancer Research, 10
-
L. Mills, D. Poller, C. Yiangou (2005)
Galectin‐3 is not useful in thyroid FNACytopathology, 16
-
Grace Yang, D. Liebeskind, A. Messina (2003)
Should cytopathologists stop reporting follicular neoplasms on fine‐needle aspiration of the thyroid?Cancer Cytopathology, 99
- Publisher
- Spandidos Publications
- Copyright
- Copyright © Spandidos Publications
- ISSN
- 1021-335X
- eISSN
- 1791-2431
- DOI
- 10.3892/or.19.2.329
- Publisher site
- See Article on Publisher Site
Abstract
It is difficult to distinguish benign from malignant follicular thyroid tumors by histological or cytological examination. The goal of this study was to reveal gene expression variations between benign and malignant follicular lesions of the thyroid gland. We investigated gene expression profiles from 24 follicular thyroid tumors (12 carcinomas and 12 adenomas) and 13 normal thyroid tissues using high-density human cDNA arrays. The identification of gene expression changes was based on signal intensity ratios of tumor versus normal thyroid parenchyma. Expression patterns of a set of known genes were found to be significantly different between follicular adenomas and follicular carcinomas. Our results demonstrate a potential use of gene expression profiling for differentiating benign from malignant follicular thyroid tumors. A detailed investigation of the differentially expressed genes could give new insights into molecular pathways of malignant transformation of thyroid follicular neoplasm and may help to develop a molecular tool for the preoperative differential diagnosis.
Journal
Oncology Reports – Spandidos Publications
Published: Feb 1, 2008