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- Publisher
- SAGE
- Copyright
- © The Author(s) 2012
- ISSN
- 0733-4648
- eISSN
- 1552-4523
- DOI
- 10.1177/0733464810384592
- Publisher site
- See Article on Publisher Site
Abstract
The current study examined prescribing patterns of anticholinergic (AC) medications and their association with cognitive function in 450 nondemented and nondelirious older adults hospitalized in a postacute extended care center. Participants completed a brief neuropsychological battery that included measures of general mental status, memory, judgment, and executive functioning as part of standard clinical care. An AC burden score was calculated for each participant based on medications taken the day of the testing using the Anticholinergic Drug Scale. Although use of AC medications was common, the majority of participants were taking medications with only minimal AC properties. AC burden and total number of AC medications were negatively correlated with age. AC burden was not associated with lower performance on any of the cognitive measures. In sum, current prescribing practices of AC medications are not associated with negative cognitive effects in a sample of older adults hospitalized in an extended care center.
Journal
Journal of Applied Gerontology – SAGE
Published: Apr 1, 2012